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broman vs TwoSampleMR

A side-by-side editorial comparison of broman and TwoSampleMR — release velocity, themes, recent moves, and the top alternatives to consider.

broman vs TwoSampleMR: at a glance

FeaturebromanTwoSampleMR
SectorAnalyticsAnalytics
Velocity score0.00.0
Sparks · 30d00
Top themesstatistics, base-graphics, utilities, r-packagemendelian-randomization, genetic-epidemiology, correctness-fixes, opengwas
Last editorial update55m ago5h ago
WebsiteVisit →Visit →

What is broman?

A statistician's personal toolbox, growing one plotting utility at a time

broman is Karl Broman's collection of personal R utilities — base-graphics plotting helpers such as grayplot, dotplot and timeplot, running-window summaries, and assorted conveniences. Recent releases alternate between small additions, like runningratio2() with an adaptive window sized to hit a target denominator, and narrow bug fixes in crayons() and jiggle(). Version 0.92 removes an include that had begun warning on CRAN.

Read the full broman trajectory →

What is TwoSampleMR?

The flagship Mendelian randomization package is auditing its own estimators, one bootstrap at a time.

TwoSampleMR is the MRC-IEU package for two-sample Mendelian randomization against OpenGWAS. Its 2026 releases are a sustained correctness review rather than feature work: 0.7.9 fixed bootstrap standard errors in mr_mode() and mr_rucker_bootstrap() that had been inflated since v0.6.30, and repaired two Rucker functions that were returning malformed objects. Point estimates were not affected by the bootstrap bug.

Read the full TwoSampleMR trajectory →

broman vs TwoSampleMR: editorial side-by-side

B
broman
ANALYTICS
0.0

A statistician's personal toolbox, growing one plotting utility at a time

◆ Current state

broman is Karl Broman's collection of personal R utilities — base-graphics plotting helpers such as grayplot, dotplot and timeplot, running-window summaries, and assorted conveniences. Recent releases alternate between small additions, like runningratio2() with an adaptive window sized to hit a target denominator, and narrow bug fixes in crayons() and jiggle(). Version 0.92 removes an include that had begun warning on CRAN.

◆ Where it's heading

The additions cluster around two themes: time-axis plotting and running-window summaries, both of which have been extended across several releases. Nothing here is planned in the usual sense — functions appear when the author needs them and bugs are fixed when they surface downstream, as jiggle() did through dotplot(). The C-level cleanup in 0.92 matches the same change made to R/qtl the same week, which is what maintaining a set of packages under one author looks like.

◆ Prediction

Both recent function additions extend existing families rather than starting new ones, so the next release is most likely another variant in the running-window or time-plotting group, or a fix surfaced by one of the author's other packages.

T
TwoSampleMR
ANALYTICS
0.0

The flagship Mendelian randomization package is auditing its own estimators, one bootstrap at a time.

◆ Current state

TwoSampleMR is the MRC-IEU package for two-sample Mendelian randomization against OpenGWAS. Its 2026 releases are a sustained correctness review rather than feature work: 0.7.9 fixed bootstrap standard errors in mr_mode() and mr_rucker_bootstrap() that had been inflated since v0.6.30, and repaired two Rucker functions that were returning malformed objects. Point estimates were not affected by the bootstrap bug.

◆ Where it's heading

The pattern across these releases is a package being read line by line — a copy-paste weight vector in ldsc_rg(), chunking that produced zero splits for short SNP lists, penalisation recycled across the wrong SNPs, dead code paths removed, and regression tests added behind each fix. Alongside it runs a mechanical modernization pass: seq_len() for loop indices, tidyr in place of reshape2, current ggplot2 idioms, and the OpenGWAS URL migration. Feature work is limited to forest plot presentation.

◆ Prediction

Expect the audit to continue through the remaining bootstrap and jackknife routines, with releases staying in the 0.7.x patch range and each fix arriving with its own regression test.

Alternatives to broman and TwoSampleMR

Other Analytics products tracked by Sparkpulse, ranked by recent ship velocity. Each card links to a full editorial trajectory and lets you pivot into a head-to-head comparison with either broman or TwoSampleMR.

See all broman alternatives → · See all TwoSampleMR alternatives →

Recent activity from broman and TwoSampleMR

Latest ship moves from both products, interleaved chronologically. ⚡ = editorial spark.

  1. 1mo agoTwoSampleMRBootstrap standard errors corrected in mode and Rucker estimators
  2. 2mo agoTwoSampleMRWrong weight vector and chunking fixes across the estimator set
  3. 2mo agoTwoSampleMRDeprecated ggplot2 idioms and dead code removed
  4. 3mo agoTwoSampleMROpenGWAS URLs migrated and Wald ratio warnings quieted
  5. 4mo agoTwoSampleMRCategorized forest plots aligned with the published figures
  6. 4mo agoTwoSampleMRFurther internal code optimizations
  7. 8mo agobromanRemove R_ext/PrtUtil.h include flagged by CRAN
  8. 10mo agobromanFix exact-name matching in crayons()
  9. 11mo agobromanFix jiggle() with factors missing levels
  10. 1y agobromanrunningratio2() uses an adaptive window
  11. 2y agobromantimeplot() added; running functions accept NAs
  12. 2y agobromantime_axis() added for date-time axis labels

Frequently asked questions

What is the difference between broman and TwoSampleMR?

They serve adjacent needs but don't currently overlap on shipped themes. broman and TwoSampleMR are shipping at a similar cadence (velocity 0.0 vs 0.0, both within Sparkpulse's "active" band). See the at-a-glance table above for a side-by-side breakdown of velocity, recent sparks, and editorial themes.

Is broman better than TwoSampleMR?

Sparkpulse doesn't pick a winner — we score release velocity, not feature parity. broman and TwoSampleMR are shipping at a similar cadence (velocity 0.0 vs 0.0, both within Sparkpulse's "active" band). For your specific use case, the alternatives sections above list other Analytics products to evaluate alongside.

What are the best alternatives to broman?

Top broman alternatives in Analytics are ranked by recent ship velocity. Browse the "broman alternatives" section above for the current picks, or visit /alternatives/broman-r for the full list with editorial commentary on each.

What are the best alternatives to TwoSampleMR?

Top TwoSampleMR alternatives in Analytics are ranked by recent ship velocity. Browse the "TwoSampleMR alternatives" section above for the current picks, or visit /alternatives/twosamplemr for the full list with editorial commentary on each.