paleobuddy
paleobuddy can now simulate trait-dependent diversification, not just birth-death.
Comparison · Analytics
protr vs SimInf
A side-by-side editorial comparison of protr and SimInf — release velocity, themes, recent moves, and the top alternatives to consider.
protr vs SimInf: at a glance
What is protr?
protr's feature set is finished; the work now is surviving Bioconductor's churn.
protr generates numerical descriptors from protein sequences for machine learning, plus alignment-based similarity between sequences. The descriptor functions have been stable for years. Recent releases divide cleanly into two kinds: extending the similarity computations to work under memory constraints, and absorbing the Bioconductor split that moved pairwise alignment out of Biostrings into pwalign.
What is SimInf?
SimInf 10.0 turns an epidemic simulator into a tool that fits models to real time series
SimInf simulates stochastic disease spread over networks of nodes, with a model parser that compiles user-specified transitions to C. Version 10.0.0 was a deliberate major break: the SimInf_pfilter S4 class and the bootstrap filtering interface were redesigned, a replicates slot was added to SimInf_model, a multi-particle variant of the split-step solver arrived, and the package gained Particle Markov Chain Monte Carlo fitting against observed time series. The follow-up 10.1.0 is a single zero-length memcpy fix found by CRAN's M1 checks.
protr vs SimInf: editorial side-by-side
protr
0.0ANALYTICS
protr's feature set is finished; the work now is surviving Bioconductor's churn.
◆ Current state
protr generates numerical descriptors from protein sequences for machine learning, plus alignment-based similarity between sequences. The descriptor functions have been stable for years. Recent releases divide cleanly into two kinds: extending the similarity computations to work under memory constraints, and absorbing the Bioconductor split that moved pairwise alignment out of Biostrings into pwalign.
◆ Where it's heading
The similarity side is where the remaining engineering goes, and it follows a consistent pattern — whatever parSeqSim() gained, crossSetSim() eventually gets. Batching, verbose progress and a disk-backed variant all arrived for the single-set case first and were mirrored for the cross-set case in 1.7-1. That is a maintainer closing feature-parity gaps rather than opening new directions, and the two most recent releases contain no user-facing change at all.
◆ Prediction
Expect the next release to react to another Bioconductor or R CMD check change, which accounts for three of the last four. The similarity functions now have parity, so there is no obvious internal backlog left.
SimInf
0.0ANALYTICS
SimInf 10.0 turns an epidemic simulator into a tool that fits models to real time series
◆ Current state
SimInf simulates stochastic disease spread over networks of nodes, with a model parser that compiles user-specified transitions to C. Version 10.0.0 was a deliberate major break: the SimInf_pfilter S4 class and the bootstrap filtering interface were redesigned, a replicates slot was added to SimInf_model, a multi-particle variant of the split-step solver arrived, and the package gained Particle Markov Chain Monte Carlo fitting against observed time series. The follow-up 10.1.0 is a single zero-length memcpy fix found by CRAN's M1 checks.
◆ Where it's heading
The package has been moving from simulation toward inference for several releases. The 9.x line built the input side — utilities for cleaning raw individual event data, variables and enumeration constants in the model parser — and 10.0.0 closed the loop by making the simulator fittable to data through PMCMC. The version number was incremented precisely because that required breaking the particle filter interface.
◆ Prediction
Fitting machinery this new usually needs a second pass on usability, so the next releases most likely focus on diagnostics and documentation around PMCMC rather than on the simulation core, which has been stable across the whole 9.x and 10.x history.
Alternatives to protr and SimInf
Other Analytics products tracked by Sparkpulse, ranked by recent ship velocity. Each card links to a full editorial trajectory and lets you pivot into a head-to-head comparison with either protr or SimInf.
geodist
geodist stays dependency-free and fast, and warns you when 'cheap' distances stop being honest.
errors
errors keeps making uncertainty print the way each scientific field expects.
CMAQ
CMAQ went global in v5.5, and has been patching that surface ever since.
enpls
enpls has not changed its statistics since 2016 — only its website, twice.
grex
grex is a lookup table with a version number — it ships when the annotation moves.
See all protr alternatives → · See all SimInf alternatives →
Recent activity from protr and SimInf
Latest ship moves from both products, interleaved chronologically. ⚡ = editorial spark.
- 9mo agoSimInfAvoid memcpy on zero-length continuous state vector
- 9mo agoSimInfPMCMC fitting arrives; particle filter interface redesigned ⚡
- 11mo agoprotrprotr 1.7-5 silences a Debian r-devel check note
- 1y agoprotrprotr 1.7-4 checks alignment dependencies upfront
- 1y agoprotrprotr 1.7-3 detects Biostrings version to find pwalign
- 2y agoprotrprotr 1.7-2 fixes citation key and vignette accessibility
- 2y agoprotrprotr 1.7-1 brings crossSetSim to parity with parSeqSim
- 2y agoSimInfDocumentation link anchors; parser dependency fix
- 2y agoSimInfModel parser gains variables and enumeration constants
- 2y agoSimInfindividual_events() added for raw event data cleaning
- 2y agoprotrprotr 1.7-0 adds crossSetSim for two-set similarity
- 3y agoSimInfConfigure script uses R to locate the compiler
Frequently asked questions
What is the difference between protr and SimInf?
They serve adjacent needs but don't currently overlap on shipped themes. protr and SimInf are shipping at a similar cadence (velocity 0.0 vs 0.0, both within Sparkpulse's "active" band). See the at-a-glance table above for a side-by-side breakdown of velocity, recent sparks, and editorial themes.
Is protr better than SimInf?
Sparkpulse doesn't pick a winner — we score release velocity, not feature parity. protr and SimInf are shipping at a similar cadence (velocity 0.0 vs 0.0, both within Sparkpulse's "active" band). For your specific use case, the alternatives sections above list other Analytics products to evaluate alongside.
What are the best alternatives to protr?
Top protr alternatives in Analytics are ranked by recent ship velocity. Browse the "protr alternatives" section above for the current picks, or visit /alternatives/protr-r for the full list with editorial commentary on each.
What are the best alternatives to SimInf?
Top SimInf alternatives in Analytics are ranked by recent ship velocity. Browse the "SimInf alternatives" section above for the current picks, or visit /alternatives/siminf-r for the full list with editorial commentary on each.