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Comparison · Analytics
oblicubes vs TwoSampleMR
A side-by-side editorial comparison of oblicubes and TwoSampleMR — release velocity, themes, recent moves, and the top alternatives to consider.
oblicubes vs TwoSampleMR: at a glance
What is oblicubes?
A tiny grid renderer for oblique-projection cubes, complete since its first release.
oblicubes draws 3D cubes and cuboids in oblique projection as grid grobs, with ggplot2 geom wrappers and a height-matrix helper for turning elevation data into coordinates. The entire feature set arrived in the initial 0.1.2 release, adapted from coolbutuseless's isocubes and cj-holmes's isocuboids. The two releases since have widened compatibility rather than added anything.
What is TwoSampleMR?
The flagship Mendelian randomization package is auditing its own estimators, one bootstrap at a time.
TwoSampleMR is the MRC-IEU package for two-sample Mendelian randomization against OpenGWAS. Its 2026 releases are a sustained correctness review rather than feature work: 0.7.9 fixed bootstrap standard errors in mr_mode() and mr_rucker_bootstrap() that had been inflated since v0.6.30, and repaired two Rucker functions that were returning malformed objects. Point estimates were not affected by the bootstrap bug.
oblicubes vs TwoSampleMR: editorial side-by-side
oblicubes
0.0ANALYTICS
A tiny grid renderer for oblique-projection cubes, complete since its first release.
◆ Current state
oblicubes draws 3D cubes and cuboids in oblique projection as grid grobs, with ggplot2 geom wrappers and a height-matrix helper for turning elevation data into coordinates. The entire feature set arrived in the initial 0.1.2 release, adapted from coolbutuseless's isocubes and cj-holmes's isocuboids. The two releases since have widened compatibility rather than added anything.
◆ Where it's heading
The package is finished and its maintainer is treating it that way. 1.0.0 removed the R 4.1 native pipe from examples specifically so earlier R versions could use it — reaching backward, not forward — and added image alt text. The only change since is swapping a deprecated dplyr call in examples.
◆ Prediction
Expect nothing beyond occasional dependency deprecation fixes; the release pattern shows a small, deliberately complete package being kept installable.
TwoSampleMR
0.0ANALYTICS
The flagship Mendelian randomization package is auditing its own estimators, one bootstrap at a time.
◆ Current state
TwoSampleMR is the MRC-IEU package for two-sample Mendelian randomization against OpenGWAS. Its 2026 releases are a sustained correctness review rather than feature work: 0.7.9 fixed bootstrap standard errors in mr_mode() and mr_rucker_bootstrap() that had been inflated since v0.6.30, and repaired two Rucker functions that were returning malformed objects. Point estimates were not affected by the bootstrap bug.
◆ Where it's heading
The pattern across these releases is a package being read line by line — a copy-paste weight vector in ldsc_rg(), chunking that produced zero splits for short SNP lists, penalisation recycled across the wrong SNPs, dead code paths removed, and regression tests added behind each fix. Alongside it runs a mechanical modernization pass: seq_len() for loop indices, tidyr in place of reshape2, current ggplot2 idioms, and the OpenGWAS URL migration. Feature work is limited to forest plot presentation.
◆ Prediction
Expect the audit to continue through the remaining bootstrap and jackknife routines, with releases staying in the 0.7.x patch range and each fix arriving with its own regression test.
Alternatives to oblicubes and TwoSampleMR
Other Analytics products tracked by Sparkpulse, ranked by recent ship velocity. Each card links to a full editorial trajectory and lets you pivot into a head-to-head comparison with either oblicubes or TwoSampleMR.
epikit
epikit narrows to field-epidemiology helpers, handing proportions to a sibling package
SimInf
SimInf 10.0 turns an epidemic simulator into a tool that fits models to real time series
mutagen
A young package porting Stata's egen row-wise helpers to the tidyverse, one function per release
broman
A statistician's personal toolbox, growing one plotting utility at a time
qtl
R/qtl is in pure custodial mode: every recent release answers a compiler, not a user
See all oblicubes alternatives → · See all TwoSampleMR alternatives →
Recent activity from oblicubes and TwoSampleMR
Latest ship moves from both products, interleaved chronologically. ⚡ = editorial spark.
- 1mo agoTwoSampleMRBootstrap standard errors corrected in mode and Rucker estimators
- 2mo agoTwoSampleMRWrong weight vector and chunking fixes across the estimator set
- 2mo agoTwoSampleMRDeprecated ggplot2 idioms and dead code removed
- 3mo agoTwoSampleMROpenGWAS URLs migrated and Wald ratio warnings quieted
- 4mo agoTwoSampleMRCategorized forest plots aligned with the published figures
- 4mo agoTwoSampleMRFurther internal code optimizations
- 6mo agooblicubesExamples updated to dplyr::reframe()
- 1y agooblicubesR 4.1 pipe removed from examples; image alt text added
- 3y agooblicubesInitial release: oblique-projection cube and cuboid grobs
Frequently asked questions
What is the difference between oblicubes and TwoSampleMR?
They serve adjacent needs but don't currently overlap on shipped themes. oblicubes and TwoSampleMR are shipping at a similar cadence (velocity 0.0 vs 0.0, both within Sparkpulse's "active" band). See the at-a-glance table above for a side-by-side breakdown of velocity, recent sparks, and editorial themes.
Is oblicubes better than TwoSampleMR?
Sparkpulse doesn't pick a winner — we score release velocity, not feature parity. oblicubes and TwoSampleMR are shipping at a similar cadence (velocity 0.0 vs 0.0, both within Sparkpulse's "active" band). For your specific use case, the alternatives sections above list other Analytics products to evaluate alongside.
What are the best alternatives to oblicubes?
Top oblicubes alternatives in Analytics are ranked by recent ship velocity. Browse the "oblicubes alternatives" section above for the current picks, or visit /alternatives/oblicubes-r for the full list with editorial commentary on each.
What are the best alternatives to TwoSampleMR?
Top TwoSampleMR alternatives in Analytics are ranked by recent ship velocity. Browse the "TwoSampleMR alternatives" section above for the current picks, or visit /alternatives/twosamplemr for the full list with editorial commentary on each.