paleobuddy
paleobuddy can now simulate trait-dependent diversification, not just birth-death.
Comparison · Analytics
gwasvcf vs SimInf
A side-by-side editorial comparison of gwasvcf and SimInf — release velocity, themes, recent moves, and the top alternatives to consider.
gwasvcf vs SimInf: at a glance
What is gwasvcf?
gwasvcf has stopped adding features and now just keeps proxy matching from failing.
gwasvcf reads and queries GWAS summary statistics stored as VCF, with LD proxy lookup as its most-used entry point. Every release in the visible window is a fix, and all but one land in or around proxy_match(). The last functional addition was gwasvcf_to_summaryset() in 0.1.2, which hands data to gwasglue2 rather than doing new work here.
What is SimInf?
SimInf 10.0 turns an epidemic simulator into a tool that fits models to real time series
SimInf simulates stochastic disease spread over networks of nodes, with a model parser that compiles user-specified transitions to C. Version 10.0.0 was a deliberate major break: the SimInf_pfilter S4 class and the bootstrap filtering interface were redesigned, a replicates slot was added to SimInf_model, a multi-particle variant of the split-step solver arrived, and the package gained Particle Markov Chain Monte Carlo fitting against observed time series. The follow-up 10.1.0 is a single zero-length memcpy fix found by CRAN's M1 checks.
gwasvcf vs SimInf: editorial side-by-side
gwasvcf
0.0ANALYTICS
gwasvcf has stopped adding features and now just keeps proxy matching from failing.
◆ Current state
gwasvcf reads and queries GWAS summary statistics stored as VCF, with LD proxy lookup as its most-used entry point. Every release in the visible window is a fix, and all but one land in or around proxy_match(). The last functional addition was gwasvcf_to_summaryset() in 0.1.2, which hands data to gwasglue2 rather than doing new work here.
◆ Where it's heading
The package is in custodial maintenance inside the MRC IEU OpenGWAS stack, and its releases are reactive: each one answers a specific user-reported failure, credited to the reporter. The 0.1.6 pattern is telling — rather than replace the proxy VCF construction, it keeps the original path and adds a fallback only for inputs that fail, so existing results are left bit-for-bit unchanged.
◆ Prediction
Expect further narrow robustness fixes to proxy_match() driven by user-reported VCF shapes; nothing in the entries suggests new analysis capability is being built here rather than in gwasglue2.
SimInf
0.0ANALYTICS
SimInf 10.0 turns an epidemic simulator into a tool that fits models to real time series
◆ Current state
SimInf simulates stochastic disease spread over networks of nodes, with a model parser that compiles user-specified transitions to C. Version 10.0.0 was a deliberate major break: the SimInf_pfilter S4 class and the bootstrap filtering interface were redesigned, a replicates slot was added to SimInf_model, a multi-particle variant of the split-step solver arrived, and the package gained Particle Markov Chain Monte Carlo fitting against observed time series. The follow-up 10.1.0 is a single zero-length memcpy fix found by CRAN's M1 checks.
◆ Where it's heading
The package has been moving from simulation toward inference for several releases. The 9.x line built the input side — utilities for cleaning raw individual event data, variables and enumeration constants in the model parser — and 10.0.0 closed the loop by making the simulator fittable to data through PMCMC. The version number was incremented precisely because that required breaking the particle filter interface.
◆ Prediction
Fitting machinery this new usually needs a second pass on usability, so the next releases most likely focus on diagnostics and documentation around PMCMC rather than on the simulation core, which has been stable across the whole 9.x and 10.x history.
Alternatives to gwasvcf and SimInf
Other Analytics products tracked by Sparkpulse, ranked by recent ship velocity. Each card links to a full editorial trajectory and lets you pivot into a head-to-head comparison with either gwasvcf or SimInf.
geodist
geodist stays dependency-free and fast, and warns you when 'cheap' distances stop being honest.
errors
errors keeps making uncertainty print the way each scientific field expects.
CMAQ
CMAQ went global in v5.5, and has been patching that surface ever since.
enpls
enpls has not changed its statistics since 2016 — only its website, twice.
grex
grex is a lookup table with a version number — it ships when the annotation moves.
See all gwasvcf alternatives → · See all SimInf alternatives →
Recent activity from gwasvcf and SimInf
Latest ship moves from both products, interleaved chronologically. ⚡ = editorial spark.
- 5mo agogwasvcfproxy_match() gains a fallback VCF construction path
- 8mo agogwasvcfproxy_match() handles multi-sample VCFs
- 9mo agoSimInfAvoid memcpy on zero-length continuous state vector
- 9mo agoSimInfPMCMC fitting arrives; particle filter interface redesigned ⚡
- 1y agogwasvcfsqlite3 declared in SystemRequirements
- 1y agogwasvcfMessage fix in get_ld_proxies()
- 2y agoSimInfDocumentation link anchors; parser dependency fix
- 2y agoSimInfModel parser gains variables and enumeration constants
- 2y agoSimInfindividual_events() added for raw event data cleaning
- 2y agogwasvcfgwasvcf_to_summaryset() bridges to gwasglue2
- 3y agoSimInfConfigure script uses R to locate the compiler
Frequently asked questions
What is the difference between gwasvcf and SimInf?
They serve adjacent needs but don't currently overlap on shipped themes. gwasvcf and SimInf are shipping at a similar cadence (velocity 0.0 vs 0.0, both within Sparkpulse's "active" band). See the at-a-glance table above for a side-by-side breakdown of velocity, recent sparks, and editorial themes.
Is gwasvcf better than SimInf?
Sparkpulse doesn't pick a winner — we score release velocity, not feature parity. gwasvcf and SimInf are shipping at a similar cadence (velocity 0.0 vs 0.0, both within Sparkpulse's "active" band). For your specific use case, the alternatives sections above list other Analytics products to evaluate alongside.
What are the best alternatives to gwasvcf?
Top gwasvcf alternatives in Analytics are ranked by recent ship velocity. Browse the "gwasvcf alternatives" section above for the current picks, or visit /alternatives/gwasvcf for the full list with editorial commentary on each.
What are the best alternatives to SimInf?
Top SimInf alternatives in Analytics are ranked by recent ship velocity. Browse the "SimInf alternatives" section above for the current picks, or visit /alternatives/siminf-r for the full list with editorial commentary on each.