gps2gtfs
gps2gtfs spent a release making its docs stop describing functions it does not have.
A side-by-side editorial comparison of glyanno and pedmut — release velocity, themes, recent moves, and the top alternatives to consider.
Glycan annotation stops depending on the database having seen the structure before.
glyanno resolves mass spectrometry observations into glycan compositions and structures, converting between m/z, composition and structure, filling in missing detail on partial structures, and mapping results to GlyTouCan accessions. The newest release adds de novo reconstruction of topological N-glycans, falling back to the topological database only when reconstruction is not possible. Batch performance was reworked at the same time, with vector inputs reusing prepared databases and direct lookups instead of repeating setup per element.
pedmut turns awkward mutation models into ones the likelihood engine can actually handle.
pedmut builds and transforms the mutation models used in pedigree likelihood calculations. Its recent arc is a toolkit of model transformations: makeReversible() with three methods, makeStationary() replacing the older stabilize(), adjustRate() for tuning overall mutation rate, and lumpMutSpecial() for lumping models that strong lumpability cannot handle. The most recent release is narrow, adding a programmatic output format to getParams().
glyanno resolves mass spectrometry observations into glycan compositions and structures, converting between m/z, composition and structure, filling in missing detail on partial structures, and mapping results to GlyTouCan accessions. The newest release adds de novo reconstruction of topological N-glycans, falling back to the topological database only when reconstruction is not possible. Batch performance was reworked at the same time, with vector inputs reusing prepared databases and direct lookups instead of repeating setup per element.
The consistent theme is making ambiguous results honest and predictable. return_best moved from returning a shortened tibble to a vector aligned with the input, with NA for unmatched glycans; matching concrete compositions against a generic database now errors instead of silently returning nothing; zero-length database arguments are rejected. Alongside that, functions belonging elsewhere have been pushed down into glyrepr rather than duplicated, which is the same boundary discipline visible across this cohort. Version churn is largely driven by upstream: two of the last six entries exist to absorb breaking changes in glyrepr.
De novo reconstruction currently covers topological N-glycans only, so extending it to other structure levels or to O-glycans is the natural next step. The performance work suggests batch annotation of full experiments is now the primary use being optimised for.
pedmut builds and transforms the mutation models used in pedigree likelihood calculations. Its recent arc is a toolkit of model transformations: makeReversible() with three methods, makeStationary() replacing the older stabilize(), adjustRate() for tuning overall mutation rate, and lumpMutSpecial() for lumping models that strong lumpability cannot handle. The most recent release is narrow, adding a programmatic output format to getParams().
The consistent goal is making models satisfy the mathematical properties downstream algorithms require. Reversibility, stationarity, and lumpability each unlock something in pedprobr, and the package keeps adding ways to coerce an arbitrary model into having them. lumpMutSpecial() is explicitly incomplete, described as covering only some cases with more possibly to follow, which sets up the main open thread.
Expect additional special lumping cases to be implemented, since the package documents the current coverage as partial and pedprobr's likelihood performance depends directly on it.
Other Analytics products tracked by Sparkpulse, ranked by recent ship velocity. Each card links to a full editorial trajectory and lets you pivot into a head-to-head comparison with either glyanno or pedmut.
gps2gtfs spent a release making its docs stop describing functions it does not have.
ducksemantics puts an ontology graph and ColBERT retrieval inside DuckDB, callable from R.
dvir keeps making disaster victim identification a single call instead of a workflow.
pedbuildr reconstructs pedigrees from DNA, and it just got much faster at the search.
forrel is getting faster at the simulations forensic kinship work actually spends its time on.
pedFamilias exists to read one legacy file format, and it has that job nearly finished.
See all glyanno alternatives → · See all pedmut alternatives →
Latest ship moves from both products, interleaved chronologically. ⚡ = editorial spark.
They serve adjacent needs but don't currently overlap on shipped themes. glyanno is currently shipping more aggressively (velocity 3.8 vs 0.0), with 1 editorial sparks in the last 30 days against 0. See the at-a-glance table above for a side-by-side breakdown of velocity, recent sparks, and editorial themes.
Sparkpulse doesn't pick a winner — we score release velocity, not feature parity. glyanno is currently shipping more aggressively (velocity 3.8 vs 0.0), with 1 editorial sparks in the last 30 days against 0. For your specific use case, the alternatives sections above list other Analytics products to evaluate alongside.
Top glyanno alternatives in Analytics are ranked by recent ship velocity. Browse the "glyanno alternatives" section above for the current picks, or visit /alternatives/glyanno for the full list with editorial commentary on each.
Top pedmut alternatives in Analytics are ranked by recent ship velocity. Browse the "pedmut alternatives" section above for the current picks, or visit /alternatives/pedmut for the full list with editorial commentary on each.