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forrel vs glyanno

A side-by-side editorial comparison of forrel and glyanno — release velocity, themes, recent moves, and the top alternatives to consider.

forrel vs glyanno: at a glance

Featureforrelglyanno
SectorAnalyticsAnalytics
Velocity score0.03.8
Sparks · 30d01
Top themesforensic genetics, kinship analysis, simulation, parallel computingglycomics, mass-spectrometry, structure-annotation, databases
Last editorial update17m ago1h ago
WebsiteVisit →Visit →

What is forrel?

forrel is getting faster at the simulations forensic kinship work actually spends its time on.

forrel handles forensic pedigree analysis: kinship likelihood ratios, profile simulation, relationship checking, and missing person calculations. Version 1.9.0 synced with pedtools 2.11.0's loop handling, which the release notes credit with enabling complex pedigrees that were previously intractable, and moved profileSim() to mirai for parallelism. It also added fEstimate() for inbreeding coefficients and parentChildLikelihood() as a fast path for the simplest case.

Read the full forrel trajectory →

What is glyanno?

Glycan annotation stops depending on the database having seen the structure before.

glyanno resolves mass spectrometry observations into glycan compositions and structures, converting between m/z, composition and structure, filling in missing detail on partial structures, and mapping results to GlyTouCan accessions. The newest release adds de novo reconstruction of topological N-glycans, falling back to the topological database only when reconstruction is not possible. Batch performance was reworked at the same time, with vector inputs reusing prepared databases and direct lookups instead of repeating setup per element.

Read the full glyanno trajectory →

forrel vs glyanno: editorial side-by-side

F
forrel
ANALYTICS
0.0

forrel is getting faster at the simulations forensic kinship work actually spends its time on.

◆ Current state

forrel handles forensic pedigree analysis: kinship likelihood ratios, profile simulation, relationship checking, and missing person calculations. Version 1.9.0 synced with pedtools 2.11.0's loop handling, which the release notes credit with enabling complex pedigrees that were previously intractable, and moved profileSim() to mirai for parallelism. It also added fEstimate() for inbreeding coefficients and parentChildLikelihood() as a fast path for the simplest case.

◆ Where it's heading

Two long threads run through the window. One is making the common operations cheap: faster simulations through reorganized likelihood calculations, a dedicated parent-child path, dropped map attribute preservation, log-likelihoods to avoid underflow in kinshipLR(). The other is making relationship checking presentable, with checkPairwise() growing ggplot2 and plotly output, verbal relationship descriptions, and bootstrap p-values. Reference data is maintained alongside both, with the FORCE SNP panel completed and an X-chromosomal counterpart added.

◆ Prediction

With profileSim() on mirai and the loop handling synced, the next likely step is extending mirai parallelism to the other simulation-heavy functions such as exclusionPower() and the bootstrap in checkPairwise().

G
glyanno
ANALYTICS
3.8

Glycan annotation stops depending on the database having seen the structure before.

◆ Current state

glyanno resolves mass spectrometry observations into glycan compositions and structures, converting between m/z, composition and structure, filling in missing detail on partial structures, and mapping results to GlyTouCan accessions. The newest release adds de novo reconstruction of topological N-glycans, falling back to the topological database only when reconstruction is not possible. Batch performance was reworked at the same time, with vector inputs reusing prepared databases and direct lookups instead of repeating setup per element.

◆ Where it's heading

The consistent theme is making ambiguous results honest and predictable. return_best moved from returning a shortened tibble to a vector aligned with the input, with NA for unmatched glycans; matching concrete compositions against a generic database now errors instead of silently returning nothing; zero-length database arguments are rejected. Alongside that, functions belonging elsewhere have been pushed down into glyrepr rather than duplicated, which is the same boundary discipline visible across this cohort. Version churn is largely driven by upstream: two of the last six entries exist to absorb breaking changes in glyrepr.

◆ Prediction

De novo reconstruction currently covers topological N-glycans only, so extending it to other structure levels or to O-glycans is the natural next step. The performance work suggests batch annotation of full experiments is now the primary use being optimised for.

Alternatives to forrel and glyanno

Other Analytics products tracked by Sparkpulse, ranked by recent ship velocity. Each card links to a full editorial trajectory and lets you pivot into a head-to-head comparison with either forrel or glyanno.

See all forrel alternatives → · See all glyanno alternatives →

Recent activity from forrel and glyanno

Latest ship moves from both products, interleaved chronologically. ⚡ = editorial spark.

  1. 24d agoglyannoDe novo reconstruction of topological N-glycans, with database fallback
  2. 1mo agoforrelmirai parallelism and faster profile simulation
  3. 3mo agoglyannoGlyTouCan accession mapping and anomeric position filling
  4. 3mo agoglyannoFixes an enhance_struc() break from glyrepr 0.11.0
  5. 4mo agoglyannoExplicit empty return from com_to_struc()
  6. 4mo agoglyannoreturn_best output aligns with input length; silent empty matches now error
  7. 5mo agoglyannoto_level parameter removed from enhance_struc()
  8. 1y agoforrelFORCE SNP panel completed and X-chromosomal set added
  9. 1y agoforrelrankProfiles() and access to special lumping
  10. 1y agoforrelacrossComps argument and readFam() unexported
  11. 1y agoforrelcheckPairwise() overhauled with p-values and new plot backends
  12. 2y agoforrelFamilias interoperability split into pedFamilias

Frequently asked questions

What is the difference between forrel and glyanno?

They serve adjacent needs but don't currently overlap on shipped themes. glyanno is currently shipping more aggressively (velocity 3.8 vs 0.0), with 1 editorial sparks in the last 30 days against 0. See the at-a-glance table above for a side-by-side breakdown of velocity, recent sparks, and editorial themes.

Is forrel better than glyanno?

Sparkpulse doesn't pick a winner — we score release velocity, not feature parity. glyanno is currently shipping more aggressively (velocity 3.8 vs 0.0), with 1 editorial sparks in the last 30 days against 0. For your specific use case, the alternatives sections above list other Analytics products to evaluate alongside.

What are the best alternatives to forrel?

Top forrel alternatives in Analytics are ranked by recent ship velocity. Browse the "forrel alternatives" section above for the current picks, or visit /alternatives/forrel for the full list with editorial commentary on each.

What are the best alternatives to glyanno?

Top glyanno alternatives in Analytics are ranked by recent ship velocity. Browse the "glyanno alternatives" section above for the current picks, or visit /alternatives/glyanno for the full list with editorial commentary on each.