nflreadr
The nflverse data loader, whose releases are dictated by the NFL calendar and CRAN's archive policy
Comparison · Analytics
qtl2fst vs rmediation
A side-by-side editorial comparison of qtl2fst and rmediation — release velocity, themes, recent moves, and the top alternatives to consider.
qtl2fst vs rmediation: at a glance
What is qtl2fst?
The out-of-memory backend for R/qtl2, feature-complete since 2020 and now purely on upkeep
qtl2fst backs R/qtl2 genotype probabilities with on-disk fst files so large crosses don't have to fit in RAM. Its defining release was 0.22 in 2020, which added calc_genoprob_fst() and genoprob_to_alleleprob_fst() to fuse calculation and storage in one step. The five releases since are documentation links, directory-creation robustness, a Windows example fix, and — in 0.32 — a change to how cores=0 is interpreted.
What is rmediation?
RMediation shipped a three-normal CDF, then found it was silently wrong.
RMediation is a long-standing CRAN package for confidence intervals on mediated effects, now built on an S7 class hierarchy. Over eight weeks it added ProductNormal3 for serial indirect effects of the form a1*a2*b, folded the engine into the existing pprodnormal naming family, and then replaced that engine outright after finding it returned wrong probabilities without warning. The dev branch is at 1.7.0; CRAN still serves 1.6.1.
qtl2fst vs rmediation: editorial side-by-side
qtl2fst
0.0ANALYTICS
The out-of-memory backend for R/qtl2, feature-complete since 2020 and now purely on upkeep
◆ Current state
qtl2fst backs R/qtl2 genotype probabilities with on-disk fst files so large crosses don't have to fit in RAM. Its defining release was 0.22 in 2020, which added calc_genoprob_fst() and genoprob_to_alleleprob_fst() to fuse calculation and storage in one step. The five releases since are documentation links, directory-creation robustness, a Windows example fix, and — in 0.32 — a change to how cores=0 is interpreted.
◆ Where it's heading
The package has settled into the role of a stable satellite of R/qtl2: it tracks the parent package's conventions rather than setting its own. The cores=0 change in 0.32 arrived alongside the identical change in qtl2convert, so the parallel-computing default is being standardized across the maintainer's packages at once. Release intervals have stretched from months to years.
◆ Prediction
Further releases will most likely mirror changes originating in R/qtl2 or CRAN checks, in the same follow-the-parent pattern as 0.24 and 0.32.
rmediation
3.8ANALYTICS
RMediation shipped a three-normal CDF, then found it was silently wrong.
◆ Current state
RMediation is a long-standing CRAN package for confidence intervals on mediated effects, now built on an S7 class hierarchy. Over eight weeks it added ProductNormal3 for serial indirect effects of the form a1*a2*b, folded the engine into the existing pprodnormal naming family, and then replaced that engine outright after finding it returned wrong probabilities without warning. The dev branch is at 1.7.0; CRAN still serves 1.6.1.
◆ Where it's heading
The package is moving from a hand-rolled numerical layer to one that checks itself: the new default integrator escalates its node count until successive rules agree, warns when it hits the cap instead of returning a number, and exposes a diagnostics argument for the convergence estimate. The correctness fix went to dev ahead of the CRAN window rather than being held for it, which suggests wrong-answer bugs are treated as release-blocking regardless of cadence. Serial mediation is where the new surface area is concentrated.
◆ Prediction
1.7.0 exists specifically to land before CRAN's 2026-08-21 update window, so the next move is a CRAN submission promoting it to main; whether hcubature survives past that as a cross-check option is the open question.
Alternatives to qtl2fst and rmediation
Other Analytics products tracked by Sparkpulse, ranked by recent ship velocity. Each card links to a full editorial trajectory and lets you pivot into a head-to-head comparison with either qtl2fst or rmediation.
susier
Fine-mapping workhorse susieR spends its releases hunting null-effect trimming bugs
UCell
A rank-based gene signature scorer that has grown by adapting to whatever object format single-cell R uses next
detectseparation
A diagnostic package that generalized past its own name, then learned to say which kind of separation it found
brglm2
A bias-reduction package reaches 1.0 by adding an estimator built for high-dimensional logistic regression
bayestools
The JAGS toolkit under RoBMA, shipping the standardization machinery its downstream rewrite needed
See all qtl2fst alternatives → · See all rmediation alternatives →
Recent activity from qtl2fst and rmediation
Latest ship moves from both products, interleaved chronologically. ⚡ = editorial spark.
- 10h agormediationv1.7.0 — pprodnormal3() correctness fix ⚡
- 1mo agoqtl2fstcores=0 now leaves one core free instead of taking all
- 1mo agormediationp_prod3() renamed into the pprodnormal family
- 1mo agormediationProductNormal3: exact CDF for a product of three normals ⚡
- 1mo agormediationmedfit reaches CRAN; Remotes pointer dropped
- 1y agoqtl2fstWindows fix for the replace_path() example
- 2y agoqtl2fstDocumentation link fix
- 4y agoqtl2fstCreates missing directories instead of erroring out
- 5y agoqtl2fstTest coverage for qtl2 functions against fst-backed probabilities
- 6y agoqtl2fstDocumentation and metadata cleanup for CRAN
Frequently asked questions
What is the difference between qtl2fst and rmediation?
They serve adjacent needs but don't currently overlap on shipped themes. rmediation is currently shipping more aggressively (velocity 3.8 vs 0.0), with 1 editorial sparks in the last 30 days against 0. See the at-a-glance table above for a side-by-side breakdown of velocity, recent sparks, and editorial themes.
Is qtl2fst better than rmediation?
Sparkpulse doesn't pick a winner — we score release velocity, not feature parity. rmediation is currently shipping more aggressively (velocity 3.8 vs 0.0), with 1 editorial sparks in the last 30 days against 0. For your specific use case, the alternatives sections above list other Analytics products to evaluate alongside.
What are the best alternatives to qtl2fst?
Top qtl2fst alternatives in Analytics are ranked by recent ship velocity. Browse the "qtl2fst alternatives" section above for the current picks, or visit /alternatives/qtl2fst for the full list with editorial commentary on each.
What are the best alternatives to rmediation?
Top rmediation alternatives in Analytics are ranked by recent ship velocity. Browse the "rmediation alternatives" section above for the current picks, or visit /alternatives/rmediation for the full list with editorial commentary on each.