EvoPhylo
EvoPhylo added BEAST2 alongside MrBayes, then went quiet for two years.
Comparison · Analytics
mrbayes vs qtl
A side-by-side editorial comparison of mrbayes and qtl — release velocity, themes, recent moves, and the top alternatives to consider.
Shared themes:r-package
mrbayes vs qtl: at a glance
What is mrbayes?
mrbayes spent 2026 auditing its own Bayesian MR estimators for coding errors.
mrbayes wraps Stan and JAGS implementations of Bayesian Mendelian randomization estimators — IVW, MR-Egger, radial Egger, and their multivariable forms. Most of the visible history is packaging work: dependency trimming, conditional examples so the package installs where JAGS will not compile, a maintainer handover. The 0.5.3 release in July 2026 breaks that pattern with a dense list of fixes inside the model code itself.
What is qtl?
R/qtl is in pure custodial mode: every recent release answers a compiler, not a user
R/qtl is the long-established R package for QTL mapping in experimental crosses, covering interval mapping, composite interval mapping, multiple-QTL model fitting and the associated cross data formats. Nothing in the recent release history adds capability. Version 1.74 removes an include that started warning on CRAN, 1.72 improves an error message in cim(), and 1.70 migrates the C code from Calloc/Realloc/Free to their R_-prefixed equivalents for R-devel.
mrbayes vs qtl: editorial side-by-side
mrbayes
0.0ANALYTICS
mrbayes spent 2026 auditing its own Bayesian MR estimators for coding errors.
◆ Current state
mrbayes wraps Stan and JAGS implementations of Bayesian Mendelian randomization estimators — IVW, MR-Egger, radial Egger, and their multivariable forms. Most of the visible history is packaging work: dependency trimming, conditional examples so the package installs where JAGS will not compile, a maintainer handover. The 0.5.3 release in July 2026 breaks that pattern with a dense list of fixes inside the model code itself.
◆ Where it's heading
The package has moved from packaging upkeep into a correctness-audit phase. 0.5.3 fixes a hardcoded three-exposure loop in MVMR-Egger reporting, a broken joint-prior branch, a sigma parameterization error in radial Egger, and several prior specifications — the profile of a maintainer reading their own model files closely rather than responding to bug reports. Platform work continues underneath: an R 4.3.0 floor inherited through a transitive dependency chain, and segfault fixes on macOS ARM.
◆ Prediction
Expect further audit-driven patches to the remaining rjags and Stan model files rather than new estimators; the fixes in 0.5.3 cluster in the Egger variants, which suggests that is where the reading is still in progress.
qtl
0.0ANALYTICS
R/qtl is in pure custodial mode: every recent release answers a compiler, not a user
◆ Current state
R/qtl is the long-established R package for QTL mapping in experimental crosses, covering interval mapping, composite interval mapping, multiple-QTL model fitting and the associated cross data formats. Nothing in the recent release history adds capability. Version 1.74 removes an include that started warning on CRAN, 1.72 improves an error message in cim(), and 1.70 migrates the C code from Calloc/Realloc/Free to their R_-prefixed equivalents for R-devel.
◆ Where it's heading
The package is being maintained, not developed. The work divides cleanly into keeping the compiled code building against successive R and toolchain versions, and fixing narrow bugs reported through the issue tracker. The C-level migrations in particular are compliance with R's tightening of its C interface rather than anything chosen. Users should read the stability as maturity: the analysis surface has been fixed for years and the maintainer is keeping it installable.
◆ Prediction
R has continued to restrict its non-API C entry points, and this package has already made two such migrations, so further compile-time compliance work is the most likely content of the next release.
Alternatives to mrbayes and qtl
Other Analytics products tracked by Sparkpulse, ranked by recent ship velocity. Each card links to a full editorial trajectory and lets you pivot into a head-to-head comparison with either mrbayes or qtl.
treespace
treespace ships once every year or two, and only when CRAN or a user forces it.
Rpath
Rpath 1.1.0 learns to read Ecopath's own files, easing migration off the desktop tool.
TAF
TAF keeps turning ICES stock assessments into reproducible, dependency-pinned projects.
parallelDist
parallelDist is in pure preservation mode — one build fix every few years.
cairo
Cairo finally catches R's graphics engine, all the way to GE API 16.
Recent activity from mrbayes and qtl
Latest ship moves from both products, interleaved chronologically. ⚡ = editorial spark.
- 1mo agomrbayesEstimator audit fixes MVMR-Egger loops and radial Egger sigma
- 8mo agoqtlRemove R_ext/PrtUtil.h include flagged by CRAN
- 8mo agoqtlClearer cim() error when multiple phenotypes are passed
- 1y agoqtlC memory calls migrated to R_Calloc/R_Realloc/R_Free
- 1y agomrbayesMVMR rjags example gated on rjags being installed
- 1y agomrbayesExamples and tests skip when rstan or rjags is missing
- 1y agomrbayespkgdown site updated
- 1y agomrbayesHelper command added for installing JAGS
- 1y agomrbayesDependency surface trimmed; maintainer handover
- 2y agoqtlFix Rprintf call and remaining compiler warnings
- 2y agoqtlFix summary.scanone() thresholds and csvs phenotype reading
- 3y agoqtlFix addint()/addcovarint() with X chromosome QTL and missing phenotypes
Frequently asked questions
What is the difference between mrbayes and qtl?
Both compete on the same themes — r-package — within Analytics. mrbayes and qtl are shipping at a similar cadence (velocity 0.0 vs 0.0, both within Sparkpulse's "active" band). See the at-a-glance table above for a side-by-side breakdown of velocity, recent sparks, and editorial themes.
Is mrbayes better than qtl?
Sparkpulse doesn't pick a winner — we score release velocity, not feature parity. mrbayes and qtl are shipping at a similar cadence (velocity 0.0 vs 0.0, both within Sparkpulse's "active" band). For your specific use case, the alternatives sections above list other Analytics products to evaluate alongside.
What are the best alternatives to mrbayes?
Top mrbayes alternatives in Analytics are ranked by recent ship velocity. Browse the "mrbayes alternatives" section above for the current picks, or visit /alternatives/mrbayes for the full list with editorial commentary on each.
What are the best alternatives to qtl?
Top qtl alternatives in Analytics are ranked by recent ship velocity. Browse the "qtl alternatives" section above for the current picks, or visit /alternatives/qtl-r for the full list with editorial commentary on each.