EvoPhylo
EvoPhylo added BEAST2 alongside MrBayes, then went quiet for two years.
Comparison · Analytics
gwasvcf vs qtl
A side-by-side editorial comparison of gwasvcf and qtl — release velocity, themes, recent moves, and the top alternatives to consider.
Shared themes:maintenance
gwasvcf vs qtl: at a glance
What is gwasvcf?
gwasvcf has stopped adding features and now just keeps proxy matching from failing.
gwasvcf reads and queries GWAS summary statistics stored as VCF, with LD proxy lookup as its most-used entry point. Every release in the visible window is a fix, and all but one land in or around proxy_match(). The last functional addition was gwasvcf_to_summaryset() in 0.1.2, which hands data to gwasglue2 rather than doing new work here.
What is qtl?
R/qtl is in pure custodial mode: every recent release answers a compiler, not a user
R/qtl is the long-established R package for QTL mapping in experimental crosses, covering interval mapping, composite interval mapping, multiple-QTL model fitting and the associated cross data formats. Nothing in the recent release history adds capability. Version 1.74 removes an include that started warning on CRAN, 1.72 improves an error message in cim(), and 1.70 migrates the C code from Calloc/Realloc/Free to their R_-prefixed equivalents for R-devel.
gwasvcf vs qtl: editorial side-by-side
gwasvcf
0.0ANALYTICS
gwasvcf has stopped adding features and now just keeps proxy matching from failing.
◆ Current state
gwasvcf reads and queries GWAS summary statistics stored as VCF, with LD proxy lookup as its most-used entry point. Every release in the visible window is a fix, and all but one land in or around proxy_match(). The last functional addition was gwasvcf_to_summaryset() in 0.1.2, which hands data to gwasglue2 rather than doing new work here.
◆ Where it's heading
The package is in custodial maintenance inside the MRC IEU OpenGWAS stack, and its releases are reactive: each one answers a specific user-reported failure, credited to the reporter. The 0.1.6 pattern is telling — rather than replace the proxy VCF construction, it keeps the original path and adds a fallback only for inputs that fail, so existing results are left bit-for-bit unchanged.
◆ Prediction
Expect further narrow robustness fixes to proxy_match() driven by user-reported VCF shapes; nothing in the entries suggests new analysis capability is being built here rather than in gwasglue2.
qtl
0.0ANALYTICS
R/qtl is in pure custodial mode: every recent release answers a compiler, not a user
◆ Current state
R/qtl is the long-established R package for QTL mapping in experimental crosses, covering interval mapping, composite interval mapping, multiple-QTL model fitting and the associated cross data formats. Nothing in the recent release history adds capability. Version 1.74 removes an include that started warning on CRAN, 1.72 improves an error message in cim(), and 1.70 migrates the C code from Calloc/Realloc/Free to their R_-prefixed equivalents for R-devel.
◆ Where it's heading
The package is being maintained, not developed. The work divides cleanly into keeping the compiled code building against successive R and toolchain versions, and fixing narrow bugs reported through the issue tracker. The C-level migrations in particular are compliance with R's tightening of its C interface rather than anything chosen. Users should read the stability as maturity: the analysis surface has been fixed for years and the maintainer is keeping it installable.
◆ Prediction
R has continued to restrict its non-API C entry points, and this package has already made two such migrations, so further compile-time compliance work is the most likely content of the next release.
Alternatives to gwasvcf and qtl
Other Analytics products tracked by Sparkpulse, ranked by recent ship velocity. Each card links to a full editorial trajectory and lets you pivot into a head-to-head comparison with either gwasvcf or qtl.
treespace
treespace ships once every year or two, and only when CRAN or a user forces it.
Rpath
Rpath 1.1.0 learns to read Ecopath's own files, easing migration off the desktop tool.
TAF
TAF keeps turning ICES stock assessments into reproducible, dependency-pinned projects.
parallelDist
parallelDist is in pure preservation mode — one build fix every few years.
cairo
Cairo finally catches R's graphics engine, all the way to GE API 16.
Recent activity from gwasvcf and qtl
Latest ship moves from both products, interleaved chronologically. ⚡ = editorial spark.
- 5mo agogwasvcfproxy_match() gains a fallback VCF construction path
- 8mo agoqtlRemove R_ext/PrtUtil.h include flagged by CRAN
- 8mo agogwasvcfproxy_match() handles multi-sample VCFs
- 8mo agoqtlClearer cim() error when multiple phenotypes are passed
- 1y agogwasvcfsqlite3 declared in SystemRequirements
- 1y agogwasvcfMessage fix in get_ld_proxies()
- 1y agoqtlC memory calls migrated to R_Calloc/R_Realloc/R_Free
- 2y agoqtlFix Rprintf call and remaining compiler warnings
- 2y agoqtlFix summary.scanone() thresholds and csvs phenotype reading
- 2y agogwasvcfgwasvcf_to_summaryset() bridges to gwasglue2
- 3y agoqtlFix addint()/addcovarint() with X chromosome QTL and missing phenotypes
Frequently asked questions
What is the difference between gwasvcf and qtl?
Both compete on the same themes — maintenance — within Analytics. gwasvcf and qtl are shipping at a similar cadence (velocity 0.0 vs 0.0, both within Sparkpulse's "active" band). See the at-a-glance table above for a side-by-side breakdown of velocity, recent sparks, and editorial themes.
Is gwasvcf better than qtl?
Sparkpulse doesn't pick a winner — we score release velocity, not feature parity. gwasvcf and qtl are shipping at a similar cadence (velocity 0.0 vs 0.0, both within Sparkpulse's "active" band). For your specific use case, the alternatives sections above list other Analytics products to evaluate alongside.
What are the best alternatives to gwasvcf?
Top gwasvcf alternatives in Analytics are ranked by recent ship velocity. Browse the "gwasvcf alternatives" section above for the current picks, or visit /alternatives/gwasvcf for the full list with editorial commentary on each.
What are the best alternatives to qtl?
Top qtl alternatives in Analytics are ranked by recent ship velocity. Browse the "qtl alternatives" section above for the current picks, or visit /alternatives/qtl-r for the full list with editorial commentary on each.