paleobuddy
paleobuddy can now simulate trait-dependent diversification, not just birth-death.
Comparison · Analytics
grex vs qtl
A side-by-side editorial comparison of grex and qtl — release velocity, themes, recent moves, and the top alternatives to consider.
grex vs qtl: at a glance
What is grex?
grex is a lookup table with a version number — it ships when the annotation moves.
grex converts the deprecated Ensembl gene IDs found in GTEx data into current gene symbols and identifiers, using org.Hs.eg.db as its reference. Its value is entirely in that bundled reference data, so a release either refreshes the mapping or does nothing to it. The 2025 release does nothing to it: GitHub Actions for the docs site, a check-note fix, and a smaller vignette.
What is qtl?
R/qtl is in pure custodial mode: every recent release answers a compiler, not a user
R/qtl is the long-established R package for QTL mapping in experimental crosses, covering interval mapping, composite interval mapping, multiple-QTL model fitting and the associated cross data formats. Nothing in the recent release history adds capability. Version 1.74 removes an include that started warning on CRAN, 1.72 improves an error message in cim(), and 1.70 migrates the C code from Calloc/Realloc/Free to their R_-prefixed equivalents for R-devel.
grex vs qtl: editorial side-by-side
grex
0.0ANALYTICS
grex is a lookup table with a version number — it ships when the annotation moves.
◆ Current state
grex converts the deprecated Ensembl gene IDs found in GTEx data into current gene symbols and identifiers, using org.Hs.eg.db as its reference. Its value is entirely in that bundled reference data, so a release either refreshes the mapping or does nothing to it. The 2025 release does nothing to it: GitHub Actions for the docs site, a check-note fix, and a smaller vignette.
◆ Where it's heading
The annotation refreshes stopped. Between 2017 and 2019 the package tracked org.Hs.eg.db through four versions and added the GTEx V7 identifier set; since then the reference has stood still while the releases turned to packaging. That gap matters more here than it would elsewhere — a stale mapping table silently returns outdated symbols rather than failing, so the package's core asset ages invisibly.
◆ Prediction
Nothing in these entries signals a planned data refresh, and the six-year pattern suggests the next release will again be infrastructure. Users needing current annotations should check which org.Hs.eg.db version is bundled rather than assume the version number reflects it.
qtl
0.0ANALYTICS
R/qtl is in pure custodial mode: every recent release answers a compiler, not a user
◆ Current state
R/qtl is the long-established R package for QTL mapping in experimental crosses, covering interval mapping, composite interval mapping, multiple-QTL model fitting and the associated cross data formats. Nothing in the recent release history adds capability. Version 1.74 removes an include that started warning on CRAN, 1.72 improves an error message in cim(), and 1.70 migrates the C code from Calloc/Realloc/Free to their R_-prefixed equivalents for R-devel.
◆ Where it's heading
The package is being maintained, not developed. The work divides cleanly into keeping the compiled code building against successive R and toolchain versions, and fixing narrow bugs reported through the issue tracker. The C-level migrations in particular are compliance with R's tightening of its C interface rather than anything chosen. Users should read the stability as maturity: the analysis surface has been fixed for years and the maintainer is keeping it installable.
◆ Prediction
R has continued to restrict its non-API C entry points, and this package has already made two such migrations, so further compile-time compliance work is the most likely content of the next release.
Alternatives to grex and qtl
Other Analytics products tracked by Sparkpulse, ranked by recent ship velocity. Each card links to a full editorial trajectory and lets you pivot into a head-to-head comparison with either grex or qtl.
geodist
geodist stays dependency-free and fast, and warns you when 'cheap' distances stop being honest.
errors
errors keeps making uncertainty print the way each scientific field expects.
CMAQ
CMAQ went global in v5.5, and has been patching that surface ever since.
enpls
enpls has not changed its statistics since 2016 — only its website, twice.
protr
protr's feature set is finished; the work now is surviving Bioconductor's churn.
Recent activity from grex and qtl
Latest ship moves from both products, interleaved chronologically. ⚡ = editorial spark.
- 8mo agoqtlRemove R_ext/PrtUtil.h include flagged by CRAN
- 8mo agoqtlClearer cim() error when multiple phenotypes are passed
- 1y agogrexgrex 1.9.1: pkgdown on Actions, smaller vignette
- 1y agoqtlC memory calls migrated to R_Calloc/R_Realloc/R_Free
- 2y agoqtlFix Rprintf call and remaining compiler warnings
- 2y agoqtlFix summary.scanone() thresholds and csvs phenotype reading
- 3y agoqtlFix addint()/addcovarint() with X chromosome QTL and missing phenotypes
- 7y agogrexgrex 1.9 refreshes the reference to org.Hs.eg.db 3.8.2
- 8y agogrexgrex 1.8 adds GTEx V7 IDs, updates to org.Hs.eg.db 3.6.0
- 8y agogrexgrex 1.7 updates the reference to org.Hs.eg.db 3.4.2
- 8y agogrexgrex 1.6 drops Google Fonts from vignettes
- 9y agogrexgrex 1.5 adds a pkgdown site and refreshes the reference
Frequently asked questions
What is the difference between grex and qtl?
They serve adjacent needs but don't currently overlap on shipped themes. grex and qtl are shipping at a similar cadence (velocity 0.0 vs 0.0, both within Sparkpulse's "active" band). See the at-a-glance table above for a side-by-side breakdown of velocity, recent sparks, and editorial themes.
Is grex better than qtl?
Sparkpulse doesn't pick a winner — we score release velocity, not feature parity. grex and qtl are shipping at a similar cadence (velocity 0.0 vs 0.0, both within Sparkpulse's "active" band). For your specific use case, the alternatives sections above list other Analytics products to evaluate alongside.
What are the best alternatives to grex?
Top grex alternatives in Analytics are ranked by recent ship velocity. Browse the "grex alternatives" section above for the current picks, or visit /alternatives/grex-r for the full list with editorial commentary on each.
What are the best alternatives to qtl?
Top qtl alternatives in Analytics are ranked by recent ship velocity. Browse the "qtl alternatives" section above for the current picks, or visit /alternatives/qtl-r for the full list with editorial commentary on each.