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Comparison · Analytics
glystats vs silx
A side-by-side editorial comparison of glystats and silx — release velocity, themes, recent moves, and the top alternatives to consider.
glystats vs silx: at a glance
What is glystats?
glystats keeps deleting analyses it decided belong somewhere else.
glystats provides the statistical tests behind glycoverse: differential analysis, clustering, dimensionality reduction, and until recently enrichment. The last four releases are mostly subtraction. WGCNA and consensus clustering were removed in 0.10.0 as too interactive for a pipeline package, the enrichment functions were deprecated in the same release and deleted in 0.11.0 in favor of glyfun, and 0.11.0 also removed every gly_*_() matrix and vector interface. What remains accepts SummarizedExperiment inputs.
What is silx?
silx settles into maintenance a release after its PySide6 migration
silx is in the quiet phase after a generational release. 3.1.1 is a single fix to FitWidget loading a fit function from file. The release before it, 3.1.0, was the first real feature work since the migration - asinh axis scaling, twilight colormaps, and dark-theme icons - and 3.0.1 was similarly small. The 3.0.0 cut that reset the Qt binding and Python floor still defines what the line is doing.
glystats vs silx: editorial side-by-side
glystats
0.0ANALYTICS
glystats keeps deleting analyses it decided belong somewhere else.
◆ Current state
glystats provides the statistical tests behind glycoverse: differential analysis, clustering, dimensionality reduction, and until recently enrichment. The last four releases are mostly subtraction. WGCNA and consensus clustering were removed in 0.10.0 as too interactive for a pipeline package, the enrichment functions were deprecated in the same release and deleted in 0.11.0 in favor of glyfun, and 0.11.0 also removed every gly_*_() matrix and vector interface. What remains accepts SummarizedExperiment inputs.
◆ Where it's heading
The package is narrowing on purpose. The through-line across removals is a refusal to support two calling conventions or two homes for the same analysis: containers only, no bare matrices; one enrichment implementation, in glyfun. The additive work in the window went to statistical rigor rather than surface area, with effect sizes added to the four main tests, sign bugs fixed, and the log2 pseudo-count reduced.
◆ Prediction
With the interface pruning finished, the next releases are more likely to deepen the tests that remain than to add new analysis families.
silx
5.0ANALYTICS
silx settles into maintenance a release after its PySide6 migration
◆ Current state
silx is in the quiet phase after a generational release. 3.1.1 is a single fix to FitWidget loading a fit function from file. The release before it, 3.1.0, was the first real feature work since the migration - asinh axis scaling, twilight colormaps, and dark-theme icons - and 3.0.1 was similarly small. The 3.0.0 cut that reset the Qt binding and Python floor still defines what the line is doing.
◆ Where it's heading
The cadence has slowed markedly since April, and the content has shifted from structural change to plotting and colormap refinement. That is the expected shape after a binding migration: downstream beamline code needs a stable target, so the project trades feature velocity for a quiet surface. The gap between 3.0.1 in May and 3.1.0 in August is the clearest signal of the deliberate slowdown.
◆ Prediction
Expect further point releases servicing the plotting and fitting widgets rather than another structural change, with feature work continuing to arrive in the 3.1.x minors rather than patches.
Alternatives to glystats and silx
Other Analytics products tracked by Sparkpulse, ranked by recent ship velocity. Each card links to a full editorial trajectory and lets you pivot into a head-to-head comparison with either glystats or silx.
Omni
Omni ships weekly, and almost every week the headline item is an AI feature.
Plotly
Plotly is turning its cloud into a metered compute platform with an enterprise on-ramp.
aniread
aniread stops asking you to know which tracker wrote the file
Rho
Rho's release machinery finally produced a stable build — and it shipped no new product.
Usermaven
Usermaven closed the loop: data comes in from anywhere, and now it goes back out.
See all glystats alternatives → · See all silx alternatives →
Recent activity from glystats and silx
Latest ship moves from both products, interleaved chronologically. ⚡ = editorial spark.
- 6h agosilxFitWidget fix for loading a fit function from file
- 9d agosilx3.1.0: asinh axis scaling, twilight colormaps, dark-theme icons
- 1mo agoglystatsDocs recommend the new SE containers
- 1mo agoglystatsTests recognize both container types consistently
- 1mo agoglystatsMatrix interfaces and enrichment functions removed
- 3mo agoglystatsSmaller log2 pseudo-count across DEA and clustering
- 3mo agosilx3.0.1: silx view fails to disable HDF5 file locking
- 3mo agoglystatsWGCNA and clustering dropped, enrichment deprecated
- 3mo agosilx3.0.0: PySide6 becomes the default Qt binding, Python 3.10 required ⚡
- 3mo agosilx3.0.0rc1: release candidate for the PySide6 migration
- 4mo agoglystatsEffect sizes added and test statistic signs fixed
- 1y agosilx2.2.2: plot axes limits, OpenGL axes and libhdf5 1.14 fixes
Frequently asked questions
What is the difference between glystats and silx?
They serve adjacent needs but don't currently overlap on shipped themes. silx is currently shipping more aggressively (velocity 5.0 vs 0.0), with 0 editorial sparks in the last 30 days against 0. See the at-a-glance table above for a side-by-side breakdown of velocity, recent sparks, and editorial themes.
Is glystats better than silx?
Sparkpulse doesn't pick a winner — we score release velocity, not feature parity. silx is currently shipping more aggressively (velocity 5.0 vs 0.0), with 0 editorial sparks in the last 30 days against 0. For your specific use case, the alternatives sections above list other Analytics products to evaluate alongside.
What are the best alternatives to glystats?
Top glystats alternatives in Analytics are ranked by recent ship velocity. Browse the "glystats alternatives" section above for the current picks, or visit /alternatives/glystats for the full list with editorial commentary on each.
What are the best alternatives to silx?
Top silx alternatives in Analytics are ranked by recent ship velocity. Browse the "silx alternatives" section above for the current picks, or visit /alternatives/silx for the full list with editorial commentary on each.