STACAS
Single-cell batch correction that learned to use cell labels, then spent three releases chasing Seurat.
A side-by-side editorial comparison of GeneNMF and rphylopic — release velocity, themes, recent moves, and the top alternatives to consider.
GeneNMF rebuilt how it derives meta-programs, changing every result it had produced.
GeneNMF applies non-negative matrix factorization to single-cell expression data to find gene programs, then consolidates programs recurring across samples into meta-programs. Version 0.6.0 replaced the consolidation method: instead of reducing each program to a gene set and taking a consensus, it retains full gene weight vectors and compares them by cosine similarity. Later releases have built reporting and control around that core — a metaprogram composition matrix showing which samples contributed, custom signature databases for enrichment testing, and the ability to drop meta-programs from results.
The R package that puts organism silhouettes on plots keeps widening where they can be drawn.
rphylopic fetches PhyloPic silhouettes and places them into R graphics — base plots, ggplot2 layers, legends, and now phylogenetic trees and igraph networks. The 1.x line has been consistent about two things: adding a new plotting context per release, and steadily replacing its early sizing vocabulary with explicit width and height arguments. Attribution handling is unusually developed for a package this size, with permalinks and per-image credit built into the retrieval functions.
GeneNMF applies non-negative matrix factorization to single-cell expression data to find gene programs, then consolidates programs recurring across samples into meta-programs. Version 0.6.0 replaced the consolidation method: instead of reducing each program to a gene set and taking a consensus, it retains full gene weight vectors and compares them by cosine similarity. Later releases have built reporting and control around that core — a metaprogram composition matrix showing which samples contributed, custom signature databases for enrichment testing, and the ability to drop meta-programs from results.
The package is moving from producing meta-programs to letting users interrogate and constrain how they were formed. Composition matrices, the drop function and downsampled similarity heatmaps all serve inspection rather than derivation. The parameters added alongside the 0.6.0 rewrite — specificity weighting, cumulative weight thresholds, confidence defined as the fraction of programs containing a gene — turn what were fixed internal choices into stated, tunable ones.
Recent releases have been fixes and compatibility work rather than method changes, so the core approach appears settled. The dependency on an RcppML version not on CRAN is the loose end most likely to force the next release.
rphylopic fetches PhyloPic silhouettes and places them into R graphics — base plots, ggplot2 layers, legends, and now phylogenetic trees and igraph networks. The 1.x line has been consistent about two things: adding a new plotting context per release, and steadily replacing its early sizing vocabulary with explicit width and height arguments. Attribution handling is unusually developed for a package this size, with permalinks and per-image credit built into the retrieval functions.
Development is expanding the set of places a silhouette can appear rather than changing what the package does. Base plots came first, then ggplot2 aesthetics and legend glyphs, then trees, then network vertices via an igraph shape registered automatically when both packages load. The other running thread is defensive maintenance against upstream churn: retries on failed API calls, fixes for ggplot2 4.0.0, and now an in-memory cache so repeated calls stop hammering the PhyloPic API. The ysize and size deprecation, opened in 1.5.0, is now complete and the arguments are scheduled for removal.
The deprecated ysize and size arguments look set to be removed in the next release, and on the pattern of the last four, another plotting context is a likelier addition than a change to the retrieval layer.
Other Analytics products tracked by Sparkpulse, ranked by recent ship velocity. Each card links to a full editorial trajectory and lets you pivot into a head-to-head comparison with either GeneNMF or rphylopic.
Single-cell batch correction that learned to use cell labels, then spent three releases chasing Seurat.
A debugger for ggplot2's internals, hardening its grip as the internals it traces keep moving.
A univariate density estimator that added zero-inflated data and reopened its C++ API to do it.
Stationary vine copulas for time series, released in lockstep with the rest of Nagler's vine stack.
A single-purpose ggplot2 extension that has spent six years tracking ggplot2 instead of growing.
A Star Trek data package that became a Memory Alpha web client and has been patching scrapers ever since.
See all GeneNMF alternatives → · See all rphylopic alternatives →
Latest ship moves from both products, interleaved chronologically. ⚡ = editorial spark.
Both compete on the same themes — r-package — within Analytics. GeneNMF and rphylopic are shipping at a similar cadence (velocity 0.0 vs 0.0, both within Sparkpulse's "active" band). See the at-a-glance table above for a side-by-side breakdown of velocity, recent sparks, and editorial themes.
Sparkpulse doesn't pick a winner — we score release velocity, not feature parity. GeneNMF and rphylopic are shipping at a similar cadence (velocity 0.0 vs 0.0, both within Sparkpulse's "active" band). For your specific use case, the alternatives sections above list other Analytics products to evaluate alongside.
Top GeneNMF alternatives in Analytics are ranked by recent ship velocity. Browse the "GeneNMF alternatives" section above for the current picks, or visit /alternatives/genenmf for the full list with editorial commentary on each.
Top rphylopic alternatives in Analytics are ranked by recent ship velocity. Browse the "rphylopic alternatives" section above for the current picks, or visit /alternatives/rphylopic for the full list with editorial commentary on each.