incase
A safer case_when that keeps hardening its guarantees while realigning to tidyverse naming.
Comparison · Analytics
GeneNMF vs mmconvert
A side-by-side editorial comparison of GeneNMF and mmconvert — release velocity, themes, recent moves, and the top alternatives to consider.
Shared themes:r-package
GeneNMF vs mmconvert: at a glance
What is GeneNMF?
GeneNMF rebuilt how it derives meta-programs, changing every result it had produced.
GeneNMF applies non-negative matrix factorization to single-cell expression data to find gene programs, then consolidates programs recurring across samples into meta-programs. Version 0.6.0 replaced the consolidation method: instead of reducing each program to a gene set and taking a consensus, it retains full gene weight vectors and compares them by cosine similarity. Later releases have built reporting and control around that core — a metaprogram composition matrix showing which samples contributed, custom signature databases for enrichment testing, and the ability to drop meta-programs from results.
What is mmconvert?
A single-purpose mouse map interpolator that solved its problem in 2023 and has coasted since
mmconvert does one thing: interpolate between GRCm39 physical positions and the revised Cox genetic map for mouse MUGA array markers. The substantive work all landed in a burst across 2021-2023 — the initial function, the GRCm39 annotation dataset, cross2_to_grcm39(), the recomputed Cox maps and their smoothed replacement. Everything since is upkeep: a warning-message fix in 0.12, and 0.14 is a test adjustment to silence a CRAN Note with no code change at all.
GeneNMF vs mmconvert: editorial side-by-side
GeneNMF
0.0ANALYTICS
GeneNMF rebuilt how it derives meta-programs, changing every result it had produced.
◆ Current state
GeneNMF applies non-negative matrix factorization to single-cell expression data to find gene programs, then consolidates programs recurring across samples into meta-programs. Version 0.6.0 replaced the consolidation method: instead of reducing each program to a gene set and taking a consensus, it retains full gene weight vectors and compares them by cosine similarity. Later releases have built reporting and control around that core — a metaprogram composition matrix showing which samples contributed, custom signature databases for enrichment testing, and the ability to drop meta-programs from results.
◆ Where it's heading
The package is moving from producing meta-programs to letting users interrogate and constrain how they were formed. Composition matrices, the drop function and downsampled similarity heatmaps all serve inspection rather than derivation. The parameters added alongside the 0.6.0 rewrite — specificity weighting, cumulative weight thresholds, confidence defined as the fraction of programs containing a gene — turn what were fixed internal choices into stated, tunable ones.
◆ Prediction
Recent releases have been fixes and compatibility work rather than method changes, so the core approach appears settled. The dependency on an RcppML version not on CRAN is the loose end most likely to force the next release.
mmconvert
0.0ANALYTICS
A single-purpose mouse map interpolator that solved its problem in 2023 and has coasted since
◆ Current state
mmconvert does one thing: interpolate between GRCm39 physical positions and the revised Cox genetic map for mouse MUGA array markers. The substantive work all landed in a burst across 2021-2023 — the initial function, the GRCm39 annotation dataset, cross2_to_grcm39(), the recomputed Cox maps and their smoothed replacement. Everything since is upkeep: a warning-message fix in 0.12, and 0.14 is a test adjustment to silence a CRAN Note with no code change at all.
◆ Where it's heading
The package has reached the natural end state of a reference-data converter — the reference data stopped moving, so the package stopped moving. Releases now arrive roughly annually and exist to keep CRAN checks green. The 0.14 release shipped the same day as sibling qtl2convert 0.36, confirming these are batch maintenance passes across the maintainer's packages rather than independent development.
◆ Prediction
Without a new mouse genome build or a revised Cox map, the next release is likely another CRAN-check accommodation rather than new functionality.
Alternatives to GeneNMF and mmconvert
Other Analytics products tracked by Sparkpulse, ranked by recent ship velocity. Each card links to a full editorial trajectory and lets you pivot into a head-to-head comparison with either GeneNMF or mmconvert.
reda
A mature recurrent-event toolkit in careful maintenance, shedding weight rather than adding surface.
TidyDensity
A distribution catalogue that grows by one family at a time, and rarely breaks anything.
cfbfastr
College football's open data client hit v2 — and now reports how many API calls you have left.
rnpn
The USA phenology data client rebuilt its entire stack and stopped handing users -9999 as a number.
rempsyc
Publication-ready psychology tables and plots, tracking APA style as closely as the software allows.
See all GeneNMF alternatives → · See all mmconvert alternatives →
Recent activity from GeneNMF and mmconvert
Latest ship moves from both products, interleaved chronologically. ⚡ = editorial spark.
- 1mo agommconvertTest adjustment to clear a CRAN Note
- 11mo agoGeneNMFSingle-sample runs fixed; gene weight definition refined
- 1y agommconvertFixes a malformed warning message in mmconvert()
- 1y agoGeneNMFMetaprogram composition exposed and custom signature DBs supported
- 1y agoGeneNMFSimilarity heatmap downsampling and meta-program removal
- 2y agoGeneNMFMeta-programs rebuilt on gene weight vectors and cosine similarity ⚡
- 2y agoGeneNMFFirst stable release published to CRAN
- 3y agommconvertOmits X chromosome positions for sex-averaged and male maps
- 3y agommconvertCRAN release adds chromosome lengths and smoothed Cox maps
- 3y agommconvertRecomputed Cox genetic maps and combined-array support
- 4y agommconvertRepoints data sources from master to main branches
Frequently asked questions
What is the difference between GeneNMF and mmconvert?
Both compete on the same themes — r-package — within Analytics. GeneNMF and mmconvert are shipping at a similar cadence (velocity 0.0 vs 0.0, both within Sparkpulse's "active" band). See the at-a-glance table above for a side-by-side breakdown of velocity, recent sparks, and editorial themes.
Is GeneNMF better than mmconvert?
Sparkpulse doesn't pick a winner — we score release velocity, not feature parity. GeneNMF and mmconvert are shipping at a similar cadence (velocity 0.0 vs 0.0, both within Sparkpulse's "active" band). For your specific use case, the alternatives sections above list other Analytics products to evaluate alongside.
What are the best alternatives to GeneNMF?
Top GeneNMF alternatives in Analytics are ranked by recent ship velocity. Browse the "GeneNMF alternatives" section above for the current picks, or visit /alternatives/genenmf for the full list with editorial commentary on each.
What are the best alternatives to mmconvert?
Top mmconvert alternatives in Analytics are ranked by recent ship velocity. Browse the "mmconvert alternatives" section above for the current picks, or visit /alternatives/mmconvert for the full list with editorial commentary on each.