svines
Stationary vine copulas for time series, released in lockstep with the rest of Nagler's vine stack.
Comparison · Analytics
GeneNMF vs glydraw
A side-by-side editorial comparison of GeneNMF and glydraw — release velocity, themes, recent moves, and the top alternatives to consider.
GeneNMF vs glydraw: at a glance
What is GeneNMF?
GeneNMF rebuilt how it derives meta-programs, changing every result it had produced.
GeneNMF applies non-negative matrix factorization to single-cell expression data to find gene programs, then consolidates programs recurring across samples into meta-programs. Version 0.6.0 replaced the consolidation method: instead of reducing each program to a gene set and taking a consensus, it retains full gene weight vectors and compares them by cosine similarity. Later releases have built reporting and control around that core — a metaprogram composition matrix showing which samples contributed, custom signature databases for enrichment testing, and the ability to drop meta-programs from results.
What is glydraw?
SNFG glycan cartoons stopped being pictures and became ggplot2 geoms, guides and axis labels.
glydraw renders glycan structures as SNFG-standard cartoons, standalone or exported in bulk, and since 0.7.0 as native ggplot2 components: geom_glycan() for observations, geom_node_glycan() for ggraph networks, guide_glycan() for legends, and scale_x_glycan() and scale_y_glycan() for discrete axes. Appearance is configured through a single reusable style object rather than scattered arguments, a consolidation that 0.8.0 made breaking. The colour handling now expects a complete SNFG palette rather than sparse per-monosaccharide overrides.
GeneNMF vs glydraw: editorial side-by-side
GeneNMF
0.0ANALYTICS
GeneNMF rebuilt how it derives meta-programs, changing every result it had produced.
◆ Current state
GeneNMF applies non-negative matrix factorization to single-cell expression data to find gene programs, then consolidates programs recurring across samples into meta-programs. Version 0.6.0 replaced the consolidation method: instead of reducing each program to a gene set and taking a consensus, it retains full gene weight vectors and compares them by cosine similarity. Later releases have built reporting and control around that core — a metaprogram composition matrix showing which samples contributed, custom signature databases for enrichment testing, and the ability to drop meta-programs from results.
◆ Where it's heading
The package is moving from producing meta-programs to letting users interrogate and constrain how they were formed. Composition matrices, the drop function and downsampled similarity heatmaps all serve inspection rather than derivation. The parameters added alongside the 0.6.0 rewrite — specificity weighting, cumulative weight thresholds, confidence defined as the fraction of programs containing a gene — turn what were fixed internal choices into stated, tunable ones.
◆ Prediction
Recent releases have been fixes and compatibility work rather than method changes, so the core approach appears settled. The dependency on an RcppML version not on CRAN is the loose end most likely to force the next release.
glydraw
6.3ANALYTICS
SNFG glycan cartoons stopped being pictures and became ggplot2 geoms, guides and axis labels.
◆ Current state
glydraw renders glycan structures as SNFG-standard cartoons, standalone or exported in bulk, and since 0.7.0 as native ggplot2 components: geom_glycan() for observations, geom_node_glycan() for ggraph networks, guide_glycan() for legends, and scale_x_glycan() and scale_y_glycan() for discrete axes. Appearance is configured through a single reusable style object rather than scattered arguments, a consolidation that 0.8.0 made breaking. The colour handling now expects a complete SNFG palette rather than sparse per-monosaccharide overrides.
◆ Where it's heading
The first half of this record is geometry correctness, fixing branch spacing, overlapping linkage annotations, core fucose collisions, triangle alignment and nested side-chain layout, because a cartoon that draws the wrong topology is worse than no cartoon. Once the drawing was trustworthy the package moved outward into ggplot2 and then inward again to consolidate its own API, dropping the glyexp dependency, removing positional argument support, and folding rendering options into style_glydraw(). Each of the last several releases has been explicitly breaking, which is a maintainer using a pre-1.0 window deliberately.
◆ Prediction
With the style object established and the ggplot2 surface in place, the remaining explicit arguments, show_linkage and orient, are the visible inconsistency and may follow the others into the style. Sibling packages adopt each change within days, as glyenzy did with the new orientation values, so expect the next breaking change to propagate the same way.
Alternatives to GeneNMF and glydraw
Other Analytics products tracked by Sparkpulse, ranked by recent ship velocity. Each card links to a full editorial trajectory and lets you pivot into a head-to-head comparison with either GeneNMF or glydraw.
gghighlight
A single-purpose ggplot2 extension that has spent six years tracking ggplot2 instead of growing.
rtrek
A Star Trek data package that became a Memory Alpha web client and has been patching scrapers ever since.
eiaapi
A thin EIA energy-data client whose whole story is making bulk queries survive the API's limits.
delaporte
A Fortran-backed Delaporte distribution package where every release is compiler and CRAN weather.
NHSRwaitinglist
Queuing theory packaged for NHS waiting-list managers, one year into a community-built first release.
See all GeneNMF alternatives → · See all glydraw alternatives →
Recent activity from GeneNMF and glydraw
Latest ship moves from both products, interleaved chronologically. ⚡ = editorial spark.
- 15d agoglydrawRendering options consolidated into a single style object
- 23d agoglydrawGlycan cartoons become ggplot2 geoms, legends and axis labels ⚡
- 1mo agoglydrawNested side-chain layout preserves residue order and linkage labels
- 1mo agoglydrawFucose triangle geometry aligned to rectangle node bounds
- 1mo agoglydrawCustom colours, fucose orientation and export scaling; glyexp dependency dropped
- 1mo agoglydrawSwitches to SNFG standard colours
- 11mo agoGeneNMFSingle-sample runs fixed; gene weight definition refined
- 1y agoGeneNMFMetaprogram composition exposed and custom signature DBs supported
- 1y agoGeneNMFSimilarity heatmap downsampling and meta-program removal
- 2y agoGeneNMFMeta-programs rebuilt on gene weight vectors and cosine similarity ⚡
- 2y agoGeneNMFFirst stable release published to CRAN
Frequently asked questions
What is the difference between GeneNMF and glydraw?
They serve adjacent needs but don't currently overlap on shipped themes. glydraw is currently shipping more aggressively (velocity 6.3 vs 0.0), with 1 editorial sparks in the last 30 days against 0. See the at-a-glance table above for a side-by-side breakdown of velocity, recent sparks, and editorial themes.
Is GeneNMF better than glydraw?
Sparkpulse doesn't pick a winner — we score release velocity, not feature parity. glydraw is currently shipping more aggressively (velocity 6.3 vs 0.0), with 1 editorial sparks in the last 30 days against 0. For your specific use case, the alternatives sections above list other Analytics products to evaluate alongside.
What are the best alternatives to GeneNMF?
Top GeneNMF alternatives in Analytics are ranked by recent ship velocity. Browse the "GeneNMF alternatives" section above for the current picks, or visit /alternatives/genenmf for the full list with editorial commentary on each.
What are the best alternatives to glydraw?
Top glydraw alternatives in Analytics are ranked by recent ship velocity. Browse the "glydraw alternatives" section above for the current picks, or visit /alternatives/glydraw for the full list with editorial commentary on each.