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Comparison · Infra & APIs

driveR vs profoc

A side-by-side editorial comparison of driveR and profoc — release velocity, themes, recent moves, and the top alternatives to consider.

Shared themes:r-package

driveR vs profoc: at a glance

FeaturedriveRprofoc
SectorInfra & APIsInfra & APIs
Velocity score0.00.0
Sparks · 30d00
Top themescancer-genomics, bioinformatics, r-package, driver-genesforecasting, online-learning, r-package, rcpp
Last editorial update1h ago1h ago
WebsiteVisit →Visit →

What is driveR?

A cancer driver prioritization package that ships rarely and mostly to stay installable

driveR prioritizes cancer driver genes from somatic variant and copy number data, combining coding impact scores, noncoding impact, copy number alteration scores and hotspot annotations into a multi-task learning classification model. Version 0.5.0 added gene-level SCNA data frames as an accepted input to create_features_df(), with an example table shipped alongside, widening the entry point beyond the segment-level format. The same release moved org.Hs.eg.db and both hg19 and hg38 TxDb annotation packages from Imports to Suggests under new CRAN policy, with dependent functions now raising an error when they are absent rather than silently degrading.

Read the full driveR trajectory →

What is profoc?

A forecast combination package that spun its profiler out into its own project

profoc combines probabilistic forecasts online, using the Bernstein online aggregation family with B-spline smoothing over quantiles and time. The recent releases are infrastructure rather than method: 1.3.4 removed a using namespace arma directive for CRAN compliance and closed a timer edge case, 1.3.3 adjusted the integration with rcpptimer against its now-stable 1.2.0 API. The last release to change what users can do was 1.3.0, which exposed the conline C++ class to R and exported init_experts_list(), make_basis_mats(), make_hat_mats() and post_process_model() so the engine can be driven directly.

Read the full profoc trajectory →

driveR vs profoc: editorial side-by-side

D
driveR
INFRA · APIS
0.0

A cancer driver prioritization package that ships rarely and mostly to stay installable

◆ Current state

driveR prioritizes cancer driver genes from somatic variant and copy number data, combining coding impact scores, noncoding impact, copy number alteration scores and hotspot annotations into a multi-task learning classification model. Version 0.5.0 added gene-level SCNA data frames as an accepted input to create_features_df(), with an example table shipped alongside, widening the entry point beyond the segment-level format. The same release moved org.Hs.eg.db and both hg19 and hg38 TxDb annotation packages from Imports to Suggests under new CRAN policy, with dependent functions now raising an error when they are absent rather than silently degrading.

◆ Where it's heading

Releases are infrequent and split cleanly between capability and correction. GRCh38 support arrived in 0.4.0 and cancer-type-specific thresholds were refreshed in 0.3.0, while the 0.2.x pair fixed scoring errors serious enough to require retraining: a column name mismatch meant the SCNA score was not being computed at all, and MCR table coordinates needed converting from hg18 to hg19. Both times the bundled classification model and thresholds were rebuilt as a consequence. Since 0.4.0 the changes have been input handling and packaging rather than method.

◆ Prediction

The move of the annotation databases to Suggests suggests a leaner install is the current priority; the entries give no indication of planned model or scoring changes.

P
profoc
INFRA · APIS
0.0

A forecast combination package that spun its profiler out into its own project

◆ Current state

profoc combines probabilistic forecasts online, using the Bernstein online aggregation family with B-spline smoothing over quantiles and time. The recent releases are infrastructure rather than method: 1.3.4 removed a using namespace arma directive for CRAN compliance and closed a timer edge case, 1.3.3 adjusted the integration with rcpptimer against its now-stable 1.2.0 API. The last release to change what users can do was 1.3.0, which exposed the conline C++ class to R and exported init_experts_list(), make_basis_mats(), make_hat_mats() and post_process_model() so the engine can be driven directly.

◆ Where it's heading

The direction is toward a reusable C++ core with thin language bindings. The timing code that lived inside profoc was extracted into the standalone rcpptimer package in 1.3.2, deliberately so other R packages and Python projects could use it through cpptimer and cppytimer, and the clock header was reworked in 1.3.1 to maximise the code shared between the R and Python versions. Method work sits earlier in the history - periodic splines and penalties in 1.2.0, the penalty() function in 1.1.0 - while the recent cadence, a single release in the last sixteen months, points at a package the maintainer considers finished.

◆ Prediction

The repeated references to future Python use suggest the next significant work happens outside this package, in the shared C++ components, rather than in profoc's R surface.

Alternatives to driveR and profoc

Other Infra & APIs products tracked by Sparkpulse, ranked by recent ship velocity. Each card links to a full editorial trajectory and lets you pivot into a head-to-head comparison with either driveR or profoc.

See all driveR alternatives → · See all profoc alternatives →

Recent activity from driveR and profoc

Latest ship moves from both products, interleaved chronologically. ⚡ = editorial spark.

  1. 6mo agoprofocCRAN compliance fix removing a namespace directive
  2. 7mo agodriveRGene-level copy number input accepted, annotation packages made optional
  3. 1y agoprofocTimer integration updated to the stable rcpptimer API
  4. 2y agoprofocTiming code extracted into the standalone rcpptimer package
  5. 2y agoprofocInteger overflow fix and Welford timing statistics
  6. 2y agoprofocThe conline C++ class opens up to R users
  7. 2y agoprofocQuantile crossing flagged and tidy methods added
  8. 3y agodriveRCRAN documentation error fixed
  9. 4y agodriveRGRCh38 genome build supported
  10. 4y agodriveRCancer-type-specific thresholds updated
  11. 5y agodriveRMCR coordinates converted to hg19 and the model retrained
  12. 5y agodriveRCopy number score was never being computed, model rebuilt

Frequently asked questions

What is the difference between driveR and profoc?

Both compete on the same themes — r-package — within Infra & APIs. driveR and profoc are shipping at a similar cadence (velocity 0.0 vs 0.0, both within Sparkpulse's "active" band). See the at-a-glance table above for a side-by-side breakdown of velocity, recent sparks, and editorial themes.

Is driveR better than profoc?

Sparkpulse doesn't pick a winner — we score release velocity, not feature parity. driveR and profoc are shipping at a similar cadence (velocity 0.0 vs 0.0, both within Sparkpulse's "active" band). For your specific use case, the alternatives sections above list other Infra & APIs products to evaluate alongside.

What are the best alternatives to driveR?

Top driveR alternatives in Infra & APIs are ranked by recent ship velocity. Browse the "driveR alternatives" section above for the current picks, or visit /alternatives/driver for the full list with editorial commentary on each.

What are the best alternatives to profoc?

Top profoc alternatives in Infra & APIs are ranked by recent ship velocity. Browse the "profoc alternatives" section above for the current picks, or visit /alternatives/profoc for the full list with editorial commentary on each.