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Comparison · Analytics
DoseFinding vs Holistics
A side-by-side editorial comparison of DoseFinding and Holistics — release velocity, themes, recent moves, and the top alternatives to consider.
DoseFinding vs Holistics: at a glance
What is DoseFinding?
New stewardship at openpharma, then two releases adding the methods MCP-Mod was missing
DoseFinding implements MCP-Mod and related dose-response methodology for clinical trial design and analysis. In 2024 it changed hands — Marius Thomas took over as maintainer, Novartis was recorded as copyright holder and funder, and the package moved to the openpharma GitHub organisation with roxygen documentation and a proper NEWS file. The two releases since have added substantive methodology: model averaging for dose-response fitting in 1.3-1, and conditional and predictive power for interim analyses in 1.4-1.
What is Holistics?
Holistics is adding governance to the AI layer it spent the summer building.
Holistics ships small, frequent notes - often one or two sentences - covering three strands at once: AI features in Explore and Chat, as-code control over presentation through AML, and workspace hygiene like file history and dark mode. The August entries turn to the AI layer's edges rather than its capabilities, with an AI user attribute for restricting what the assistant can reach. Several entries are barely a line long, so scope frequently has to be read from the headline.
DoseFinding vs Holistics: editorial side-by-side
DoseFinding
0.0ANALYTICS
New stewardship at openpharma, then two releases adding the methods MCP-Mod was missing
◆ Current state
DoseFinding implements MCP-Mod and related dose-response methodology for clinical trial design and analysis. In 2024 it changed hands — Marius Thomas took over as maintainer, Novartis was recorded as copyright holder and funder, and the package moved to the openpharma GitHub organisation with roxygen documentation and a proper NEWS file. The two releases since have added substantive methodology: model averaging for dose-response fitting in 1.3-1, and conditional and predictive power for interim analyses in 1.4-1.
◆ Where it's heading
The pattern before the handover was maintenance — R-devel compliance, a bug fix, a link. After it, each release carries a named methodological addition with an acknowledged contributor, plus documentation to match: a longitudinal analysis vignette shipped alongside the interim power work. Housekeeping continues underneath, mostly clearing deprecated ggplot2 interfaces, aes_string in one release and qplot in the next.
◆ Prediction
Given the last two releases each added one method with a supporting vignette, expect the next to follow the same shape. Both additions so far extend the package beyond fixed dose-response fitting, so adaptive and interim methodology is the more likely direction.
Holistics
5.0ANALYTICS
Holistics is adding governance to the AI layer it spent the summer building.
◆ Current state
Holistics ships small, frequent notes - often one or two sentences - covering three strands at once: AI features in Explore and Chat, as-code control over presentation through AML, and workspace hygiene like file history and dark mode. The August entries turn to the AI layer's edges rather than its capabilities, with an AI user attribute for restricting what the assistant can reach. Several entries are barely a line long, so scope frequently has to be read from the headline.
◆ Where it's heading
The AI work has moved through a recognizable sequence: capability first with chart suggestions, then observability with AI Chat Insights for admins, and now access control with an AI-specific user attribute. Alongside it, Holistics keeps pulling presentation into AML - custom charts, theme palettes, currency formats - so the things analysts used to click are versioned as code. File history is the join between the two threads, giving every dashboard, model, and dataset its own restorable timeline.
◆ Prediction
With capability, visibility, and access control now in place for the AI layer, the next step is likely audit or policy depth - logging what the assistant answered against which data - rather than new AI surfaces.
Alternatives to DoseFinding and Holistics
Other Analytics products tracked by Sparkpulse, ranked by recent ship velocity. Each card links to a full editorial trajectory and lets you pivot into a head-to-head comparison with either DoseFinding or Holistics.
Omni
Omni ships weekly, and almost every week the headline item is an AI feature.
silx
silx settles into maintenance a release after its PySide6 migration
Plotly
Plotly is turning its cloud into a metered compute platform with an enterprise on-ramp.
aniread
aniread stops asking you to know which tracker wrote the file
Rho
Rho's release machinery finally produced a stable build — and it shipped no new product.
See all DoseFinding alternatives → · See all Holistics alternatives →
Recent activity from DoseFinding and Holistics
Latest ship moves from both products, interleaved chronologically. ⚡ = editorial spark.
- 2d agoHolisticsAI user attribute restricts AI access to sensitive data
- 16d agoHolisticsCustom currency and unit formats, per field
- 19d agoHolisticsFile history: per-file version timeline and restore
- 22d agoHolisticsCustom charts become AML code with GUI authoring
- 23d agoHolisticsColor palettes can be assigned at the theme level
- 27d agoHolisticsDate-range presets and typed shorthands
- 1y agoDoseFindingConditional and predictive power for interim analyses
- 1y agoDoseFindingModel averaging arrives for dose-response fitting ⚡
- 1y agoDoseFindingPackage moves to openpharma under new maintainership
- 2y agoDoseFindingCompliance update for R-devel
- 3y agoDoseFindingpowMCTBinCount bug fix
Frequently asked questions
What is the difference between DoseFinding and Holistics?
They serve adjacent needs but don't currently overlap on shipped themes. Holistics is currently shipping more aggressively (velocity 5.0 vs 0.0), with 0 editorial sparks in the last 30 days against 0. See the at-a-glance table above for a side-by-side breakdown of velocity, recent sparks, and editorial themes.
Is DoseFinding better than Holistics?
Sparkpulse doesn't pick a winner — we score release velocity, not feature parity. Holistics is currently shipping more aggressively (velocity 5.0 vs 0.0), with 0 editorial sparks in the last 30 days against 0. For your specific use case, the alternatives sections above list other Analytics products to evaluate alongside.
What are the best alternatives to DoseFinding?
Top DoseFinding alternatives in Analytics are ranked by recent ship velocity. Browse the "DoseFinding alternatives" section above for the current picks, or visit /alternatives/dosefinding for the full list with editorial commentary on each.
What are the best alternatives to Holistics?
Top Holistics alternatives in Analytics are ranked by recent ship velocity. Browse the "Holistics alternatives" section above for the current picks, or visit /alternatives/holistics for the full list with editorial commentary on each.