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collapse vs TwoSampleMR

A side-by-side editorial comparison of collapse and TwoSampleMR — release velocity, themes, recent moves, and the top alternatives to consider.

collapse vs TwoSampleMR: at a glance

FeaturecollapseTwoSampleMR
SectorAnalyticsAnalytics
Velocity score0.00.0
Sparks · 30d00
Top themesdata-transformation, performance, simd, grouped-statisticsmendelian-randomization, genetic-epidemiology, correctness-fixes, opengwas
Last editorial update1h ago2h ago
WebsiteVisit →Visit →

What is collapse?

collapse got a JSS paper and a 7x fmean speedup in the same release.

collapse provides fast grouped statistical computing and data transformation for R, built on a C backend with its own grouping, hashing and aggregation primitives. The 2.1.x line is a maintenance and optimization series: SIMD multiple-accumulator work delivering roughly 2x on fsum() and 7x on fmean() for systems without OpenMP, a custom internal unlist() with better attribute preservation, and a steady stream of correctness fixes in collap(), pivot() and roworderv().

Read the full collapse trajectory →

What is TwoSampleMR?

The flagship Mendelian randomization package is auditing its own estimators, one bootstrap at a time.

TwoSampleMR is the MRC-IEU package for two-sample Mendelian randomization against OpenGWAS. Its 2026 releases are a sustained correctness review rather than feature work: 0.7.9 fixed bootstrap standard errors in mr_mode() and mr_rucker_bootstrap() that had been inflated since v0.6.30, and repaired two Rucker functions that were returning malformed objects. Point estimates were not affected by the bootstrap bug.

Read the full TwoSampleMR trajectory →

collapse vs TwoSampleMR: editorial side-by-side

C
collapse
ANALYTICS
0.0

collapse got a JSS paper and a 7x fmean speedup in the same release.

◆ Current state

collapse provides fast grouped statistical computing and data transformation for R, built on a C backend with its own grouping, hashing and aggregation primitives. The 2.1.x line is a maintenance and optimization series: SIMD multiple-accumulator work delivering roughly 2x on fsum() and 7x on fmean() for systems without OpenMP, a custom internal unlist() with better attribute preservation, and a steady stream of correctness fixes in collap(), pivot() and roworderv().

◆ Where it's heading

The package is consolidating institutionally as much as technically. The repository moved to the fastverse organization with multiple people granted access, the Journal of Statistical Software paper landed as the primary citation, and documentation now includes an AI-generated interactive layer. Technically the focus is the hashing and grouping core — the decision to treat -0 and 0 as equal across funique(), group(), fmatch(), fmode() and their derivatives was made in sync with an equivalent change in Rcpp, and accepted a measured 3% cost to get it. The last release with breaking changes sits outside this six-entry window.

◆ Prediction

Expect further targeted performance work on the grouped statistical functions and continued small correctness fixes; the governance move to fastverse suggests contribution volume rather than direction is what the maintainer is managing.

T
TwoSampleMR
ANALYTICS
0.0

The flagship Mendelian randomization package is auditing its own estimators, one bootstrap at a time.

◆ Current state

TwoSampleMR is the MRC-IEU package for two-sample Mendelian randomization against OpenGWAS. Its 2026 releases are a sustained correctness review rather than feature work: 0.7.9 fixed bootstrap standard errors in mr_mode() and mr_rucker_bootstrap() that had been inflated since v0.6.30, and repaired two Rucker functions that were returning malformed objects. Point estimates were not affected by the bootstrap bug.

◆ Where it's heading

The pattern across these releases is a package being read line by line — a copy-paste weight vector in ldsc_rg(), chunking that produced zero splits for short SNP lists, penalisation recycled across the wrong SNPs, dead code paths removed, and regression tests added behind each fix. Alongside it runs a mechanical modernization pass: seq_len() for loop indices, tidyr in place of reshape2, current ggplot2 idioms, and the OpenGWAS URL migration. Feature work is limited to forest plot presentation.

◆ Prediction

Expect the audit to continue through the remaining bootstrap and jackknife routines, with releases staying in the 0.7.x patch range and each fix arriving with its own regression test.

Alternatives to collapse and TwoSampleMR

Other Analytics products tracked by Sparkpulse, ranked by recent ship velocity. Each card links to a full editorial trajectory and lets you pivot into a head-to-head comparison with either collapse or TwoSampleMR.

See all collapse alternatives → · See all TwoSampleMR alternatives →

Recent activity from collapse and TwoSampleMR

Latest ship moves from both products, interleaved chronologically. ⚡ = editorial spark.

  1. 1mo agoTwoSampleMRBootstrap standard errors corrected in mode and Rucker estimators
  2. 2mo agoTwoSampleMRWrong weight vector and chunking fixes across the estimator set
  3. 2mo agoTwoSampleMRDeprecated ggplot2 idioms and dead code removed
  4. 2mo agocollapseSIMD accumulators give fmean a 7x speedup without OpenMP
  5. 3mo agoTwoSampleMROpenGWAS URLs migrated and Wald ratio warnings quieted
  6. 4mo agoTwoSampleMRCategorized forest plots aligned with the published figures
  7. 4mo agoTwoSampleMRFurther internal code optimizations
  8. 7mo agocollapseNegative zero now hashes equal to zero across the package
  9. 8mo agocollapsecollap() no longer double-aggregates external weights
  10. 9mo agocollapseCustom unlist() preserves attributes
  11. 0y agocollapseAssorted bug fixes
  12. 1y agocollapsena_insert gains by-reference mode; gsplit and pivot speed up

Frequently asked questions

What is the difference between collapse and TwoSampleMR?

They serve adjacent needs but don't currently overlap on shipped themes. collapse and TwoSampleMR are shipping at a similar cadence (velocity 0.0 vs 0.0, both within Sparkpulse's "active" band). See the at-a-glance table above for a side-by-side breakdown of velocity, recent sparks, and editorial themes.

Is collapse better than TwoSampleMR?

Sparkpulse doesn't pick a winner — we score release velocity, not feature parity. collapse and TwoSampleMR are shipping at a similar cadence (velocity 0.0 vs 0.0, both within Sparkpulse's "active" band). For your specific use case, the alternatives sections above list other Analytics products to evaluate alongside.

What are the best alternatives to collapse?

Top collapse alternatives in Analytics are ranked by recent ship velocity. Browse the "collapse alternatives" section above for the current picks, or visit /alternatives/collapse-r for the full list with editorial commentary on each.

What are the best alternatives to TwoSampleMR?

Top TwoSampleMR alternatives in Analytics are ranked by recent ship velocity. Browse the "TwoSampleMR alternatives" section above for the current picks, or visit /alternatives/twosamplemr for the full list with editorial commentary on each.