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Comparison · Infra & APIs

cofad vs PowerTOST

A side-by-side editorial comparison of cofad and PowerTOST — release velocity, themes, recent moves, and the top alternatives to consider.

Shared themes:maintenance

cofad vs PowerTOST: at a glance

FeaturecofadPowerTOST
SectorInfra & APIsInfra & APIs
Velocity score0.00.0
Sparks · 30d00
Top themescontrast-analysis, factorial-designs, shiny, psychology-methodsbioequivalence, sample-size, regulatory, pharmacometrics
Last editorial update2h ago2h ago
WebsiteVisit →Visit →

What is cofad?

Contrast analysis with a Shiny front end, shipping about one release a year

cofad performs contrast analyses for factorial designs in both between- and within-subject forms, and ships a Shiny GUI alongside the R interface. The 0.3.0 release in 2024 was the substantial one: a helper for calculating differences between two sets of lambdas for competing contrast analysis, improved summary output, removal of the plyr dependency, a rebuilt Shiny interface using standard elements after the sortable drag-and-drop proved unstable, and a change of maintainer to Johannes Titz. The most recent release is a one-line patch fixing degrees of freedom in the t-test table.

Read the full cofad trajectory →

What is PowerTOST?

A bioequivalence sample-size workhorse whose news is which regulator it now covers

PowerTOST computes power and sample size for bioequivalence and its changelog reads as a record of regulatory divergence more than statistical development. Version 1.5-3 added the Gulf Co-operation Council as a regulator setting; 1.5-4 and 1.5-6 stripped 'FDA' out of the narrow-therapeutic-index function names once China's CDE began requiring the same evaluation. The most recent release, 1.5-7, is a single fix to how nvec() splits a total sample size across sequences.

Read the full PowerTOST trajectory →

cofad vs PowerTOST: editorial side-by-side

C
cofad
INFRA · APIS
0.0

Contrast analysis with a Shiny front end, shipping about one release a year

◆ Current state

cofad performs contrast analyses for factorial designs in both between- and within-subject forms, and ships a Shiny GUI alongside the R interface. The 0.3.0 release in 2024 was the substantial one: a helper for calculating differences between two sets of lambdas for competing contrast analysis, improved summary output, removal of the plyr dependency, a rebuilt Shiny interface using standard elements after the sortable drag-and-drop proved unstable, and a change of maintainer to Johannes Titz. The most recent release is a one-line patch fixing degrees of freedom in the t-test table.

◆ Where it's heading

Development is slow and correctness-led. The record runs from a JOSS publication in 2021 through a near three-year gap to a release that both extended the method and repaired the GUI, then a degrees-of-freedom fix. Maintainer and author order changed in 0.3.0, which typically marks a handover rather than a burst of new work, and the cadence since is consistent with that.

◆ Prediction

Expect low-frequency correctness releases; the competing contrast analysis helper added in 0.3.0 is the most likely thing to be extended if anything is.

P
PowerTOST
INFRA · APIS
0.0

A bioequivalence sample-size workhorse whose news is which regulator it now covers

◆ Current state

PowerTOST computes power and sample size for bioequivalence and its changelog reads as a record of regulatory divergence more than statistical development. Version 1.5-3 added the Gulf Co-operation Council as a regulator setting; 1.5-4 and 1.5-6 stripped 'FDA' out of the narrow-therapeutic-index function names once China's CDE began requiring the same evaluation. The most recent release, 1.5-7, is a single fix to how nvec() splits a total sample size across sequences.

◆ Where it's heading

The package is in long maintenance with a widening regulatory surface: the statistical methods are settled, and releases arrive when an agency publishes a framework that can be expressed as a settings variant of an existing method. Function naming has been deliberately decoupled from any single agency, with the deprecated FDA-suffixed aliases carried for years before removal. Cadence has slowed to roughly one release every eighteen months.

◆ Prediction

The next release is most likely another regulator setting or a small fix; on the deprecation notice already given, the power.NTIDFDA()-style aliases are the obvious removal candidate.

Alternatives to cofad and PowerTOST

Other Infra & APIs products tracked by Sparkpulse, ranked by recent ship velocity. Each card links to a full editorial trajectory and lets you pivot into a head-to-head comparison with either cofad or PowerTOST.

See all cofad alternatives → · See all PowerTOST alternatives →

Recent activity from cofad and PowerTOST

Latest ship moves from both products, interleaved chronologically. ⚡ = editorial spark.

  1. 10mo agoPowerTOSTFix for splitting total sample size across sequences
  2. 1y agocofadDegrees of freedom corrected in the t-test table
  3. 2y agocofadCompeting contrast helper, rebuilt Shiny GUI, maintainer change
  4. 2y agoPowerTOSTNTID functions renamed off the FDA acronym; GCC guidance in vignettes
  5. 4y agoPowerTOSTpower.NTID() aliases added; FDA-suffixed names deprecated
  6. 4y agocofadDocumentation and references for JOSS publication
  7. 4y agocofadShiny GUI added; aggregated-data function and 0-variance fix
  8. 5y agoPowerTOSTGulf Co-operation Council added as a regulator setting
  9. 5y agoPowerTOSTMaintenance release with vignette and documentation clarifications
  10. 5y agoPowerTOSTstringsAsFactors fix for older R in a vignette example

Frequently asked questions

What is the difference between cofad and PowerTOST?

Both compete on the same themes — maintenance — within Infra & APIs. cofad and PowerTOST are shipping at a similar cadence (velocity 0.0 vs 0.0, both within Sparkpulse's "active" band). See the at-a-glance table above for a side-by-side breakdown of velocity, recent sparks, and editorial themes.

Is cofad better than PowerTOST?

Sparkpulse doesn't pick a winner — we score release velocity, not feature parity. cofad and PowerTOST are shipping at a similar cadence (velocity 0.0 vs 0.0, both within Sparkpulse's "active" band). For your specific use case, the alternatives sections above list other Infra & APIs products to evaluate alongside.

What are the best alternatives to cofad?

Top cofad alternatives in Infra & APIs are ranked by recent ship velocity. Browse the "cofad alternatives" section above for the current picks, or visit /alternatives/cofad for the full list with editorial commentary on each.

What are the best alternatives to PowerTOST?

Top PowerTOST alternatives in Infra & APIs are ranked by recent ship velocity. Browse the "PowerTOST alternatives" section above for the current picks, or visit /alternatives/powertost for the full list with editorial commentary on each.