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Comparison · Infra & APIs

campsis vs PEIMAN2

A side-by-side editorial comparison of campsis and PEIMAN2 — release velocity, themes, recent moves, and the top alternatives to consider.

campsis vs PEIMAN2: at a glance

FeaturecampsisPEIMAN2
SectorInfra & APIsInfra & APIs
Velocity score3.80.0
Sparks · 30d10
Top themespharmacometrics, clinical-trial-simulation, breaking-changes, json-interfaceproteomics, post-translational-modification, enrichment-analysis, reproducibility
Last editorial update4h ago1h ago
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What is campsis?

Campsis breaks its API on purpose: snake_case throughout, RxODE compatibility cut loose.

Campsis runs clinical-trial simulations from pharmacometric models, sitting on mrgsolve and rxode2 as interchangeable engines, with the sibling package Campsismod supplying the model object layer. Version 1.9.0 is the release where the suite stops carrying its history: the whole API migrates to snake_case, backward compatibility with the old RxODE package is removed, and result processing is refactored into output functions that can be applied as a collection, with an NCA table the first substantial one. Campsismod made the same snake_case move a week earlier, so this is a suite-wide rename rather than one package's decision.

Read the full campsis trajectory →

What is PEIMAN2?

PEIMAN2 cut its annotation database loose from its release cycle without breaking CRAN.

PEIMAN2 does enrichment analysis over post-translational modifications, testing whether a protein list is enriched for particular PTMs against UniProt-derived annotations, with translation functions bridging to mass spectrometry workflows. Its answers are only as current as its bundled database, and until June that database could only be refreshed by releasing a new package version. Version 1.1.0 changes that.

Read the full PEIMAN2 trajectory →

campsis vs PEIMAN2: editorial side-by-side

C
campsis
INFRA · APIS
3.8

Campsis breaks its API on purpose: snake_case throughout, RxODE compatibility cut loose.

◆ Current state

Campsis runs clinical-trial simulations from pharmacometric models, sitting on mrgsolve and rxode2 as interchangeable engines, with the sibling package Campsismod supplying the model object layer. Version 1.9.0 is the release where the suite stops carrying its history: the whole API migrates to snake_case, backward compatibility with the old RxODE package is removed, and result processing is refactored into output functions that can be applied as a collection, with an NCA table the first substantial one. Campsismod made the same snake_case move a week earlier, so this is a suite-wide rename rather than one package's decision.

◆ Where it's heading

The 1.8 and 1.9 releases together describe a package being made drivable from outside R. JSON interfaces arrived first for models in Campsismod 1.3.0 and for datasets in Campsis 1.8.0, then extended to scenarios, settings and study replication; the output side has now been generalised the same way, from fixed result processing to a collection of output functions applied to simulated results. Renaming every function and cutting RxODE loose is the cost of that consolidation, paid in one deliberate breaking release rather than spread across several.

◆ Prediction

With the rename and the RxODE removal behind it, the next releases should restore the rxode2 engine to the test suite, which 1.9.0 removed temporarily, and continue filling out the output-function catalogue beyond NCA. The JSON surface looks like the intended entry point for driving Campsis from outside R, though the entries do not say what is meant to consume it.

P
PEIMAN2
INFRA · APIS
0.0

PEIMAN2 cut its annotation database loose from its release cycle without breaking CRAN.

◆ Current state

PEIMAN2 does enrichment analysis over post-translational modifications, testing whether a protein list is enriched for particular PTMs against UniProt-derived annotations, with translation functions bridging to mass spectrometry workflows. Its answers are only as current as its bundled database, and until June that database could only be refreshed by releasing a new package version. Version 1.1.0 changes that.

◆ Where it's heading

The package has been moving from a fixed snapshot toward versioned, user-selectable data. Earlier releases updated the bundled database in place — 1.0.0 shipped the March 2025 version and said little else — which meant the annotation vintage was whatever the package version implied. Now update_peiman_database() downloads and caches external database files and UniProt PTM lists, enrichment workflows take a database_version argument, and the mass-spec translators take a ptmlist_version, so an analysis can pin a dated database rather than a package release. The CRAN-safe default is preserved deliberately: loading, examples and checks still use the bundled internal data and need no network.

◆ Prediction

Version pinning is now expressible but the release notes do not describe how a chosen version is recorded in output, so surfacing the active database version in results is the natural companion. The database and the UniProt PTM list are versioned separately, which leaves room for a combined manifest.

Alternatives to campsis and PEIMAN2

Other Infra & APIs products tracked by Sparkpulse, ranked by recent ship velocity. Each card links to a full editorial trajectory and lets you pivot into a head-to-head comparison with either campsis or PEIMAN2.

See all campsis alternatives → · See all PEIMAN2 alternatives →

Recent activity from campsis and PEIMAN2

Latest ship moves from both products, interleaved chronologically. ⚡ = editorial spark.

  1. 15d agocampsissnake_case across the API; RxODE compatibility removed
  2. 2mo agoPEIMAN2Database updates decouple from package releases
  3. 5mo agocampsisJSON arguments reach Dataset, Scenarios and Settings
  4. 7mo agocampsisMaintenance release for future package warnings
  5. 7mo agocampsisJSON import for Campsis datasets
  6. 1y agoPEIMAN2Bundled database refreshed to the March 2025 UniProt vintage
  7. 1y agoPEIMAN2Documentation fix for the second example dataset
  8. 1y agocampsisDosing gains vectorized compartments and cycle repetition
  9. 1y agocampsisParameter uncertainty from SIR and bootstrap output
  10. 2y agoPEIMAN2Background lists for SEA and PSEA; tidyverse dependency dropped

Frequently asked questions

What is the difference between campsis and PEIMAN2?

They serve adjacent needs but don't currently overlap on shipped themes. campsis is currently shipping more aggressively (velocity 3.8 vs 0.0), with 1 editorial sparks in the last 30 days against 0. See the at-a-glance table above for a side-by-side breakdown of velocity, recent sparks, and editorial themes.

Is campsis better than PEIMAN2?

Sparkpulse doesn't pick a winner — we score release velocity, not feature parity. campsis is currently shipping more aggressively (velocity 3.8 vs 0.0), with 1 editorial sparks in the last 30 days against 0. For your specific use case, the alternatives sections above list other Infra & APIs products to evaluate alongside.

What are the best alternatives to campsis?

Top campsis alternatives in Infra & APIs are ranked by recent ship velocity. Browse the "campsis alternatives" section above for the current picks, or visit /alternatives/campsis for the full list with editorial commentary on each.

What are the best alternatives to PEIMAN2?

Top PEIMAN2 alternatives in Infra & APIs are ranked by recent ship velocity. Browse the "PEIMAN2 alternatives" section above for the current picks, or visit /alternatives/peiman2 for the full list with editorial commentary on each.