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TLF-Library

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R package TLF-Library by Open-Systems-Pharmacology — release notes from GitHub.

github.com/Open-Systems-Pharmacology/TLF-Library ↗

The Open Systems Pharmacology plotting layer spent 2025 absorbing a ggplot2 major break.

pharmacometricsggplot2plottingscientific-reportingapi-rename
◆Current state
tlf is the plotting library behind Open Systems Pharmacology's tables, listings and figures — a ggplot2 wrapper producing the PK/PD reporting output the OSP suite generates. Recent work splits into two strands: a feature set adding Lower Limit Of Quantification annotation to time-profile and observed-vs-predicted plots alongside a reworked axis-limits API, and then hot fixes to survive ggplot2 v4.0.0's breaking changes. The axis change is the substantive one, separating cropping the view from filtering the data behind it.
◆Where it's heading
The library is maturing into a stable reporting dependency rather than growing new plot types — the newest releases are watermark placement, log-tick safety and upstream compatibility, not new figures. Its exposure is to ggplot2: v4.0.0 required same-day hot fixes, which is the risk profile of a wrapper this thin. Note that this feed's version numbers and publication stamps disagree, with 1.5.170 stamped four months before the lower-numbered 1.5.158, so the release order has to be read from version numbers and the changelog ranges rather than from the feed order.
◆Prediction
With the ggplot2 v4 fallout patched and the LLOQ work promoted to a stable 1.6 line, the next releases most likely continue as small rendering fixes. Nothing in these entries points to a new plot class in progress.

◆Recent moves

  1. 9mo ago

    Watermark positioning decoupled from plot scales

    Two small rendering fixes — watermark position no longer depends on scales, and log ticks are handled more safely. Maintenance on a library that has settled into its shape.

    View source ↗
  2. 11mo ago

    Hot fixes for ggplot2 v4.0.0 breaking changes

    A one-line release that matters more than its length: ggplot2's v4.0.0 broke the library and this restored it. For a wrapper this close to its upstream, keeping pace with a major ggplot2 release is the maintenance burden that defines the package.

    View source ↗
  3. 11mo ago

    LLOQ annotation and axis cropping split from data filtering

    The stable 1.6.0 release carrying the LLOQ and axis-limits work that the 1.5.x development builds had already introduced. Its own contribution is the promotion and the renamed arguments becoming the supported API rather than new capability.

    View source ↗
  4. 1y ago

    Dev build introducing LLOQ plots and the xAxisLimits rename

    The build where the LLOQ annotation and the axis-limits rework actually landed, per its changelog range back to 1.5.125. Renaming xLimits to xAxisLimits while adding xValuesLimits draws a distinction the old API blurred: cropping the axis while keeping all data, versus filtering the data the plot is built from.

    View source ↗
  5. 1y ago

    Error-bar cap fixes atop a restated feature list

    The body restates the LLOQ and axis-limits list already delivered in the neighbouring development build, so its own delta is the error-bar cap fixes. Sizing caps only when error bars are drawn is a rendering correction, not new capability.

    View source ↗
  6. 1y ago

    Dual-axis plots stop tripping cowplot

    An internal fix to dual-axis handling with the release note stating there is no visible difference in the figures. Documentation and test snapshots updated alongside.

    View source ↗