← Back to home
Comparison · Analytics

rmediation vs scTypeEval

A side-by-side editorial comparison of rmediation and scTypeEval — release velocity, themes, recent moves, and the top alternatives to consider.

Shared themes:r package

rmediation vs scTypeEval: at a glance

FeaturermediationscTypeEval
SectorAnalyticsAnalytics
Velocity score3.80.0
Sparks · 30d10
Top themesmediation analysis, numerical integration, correctness, s7 classessingle-cell, cell type annotation, bioconductor, clustering evaluation
Last editorial update54m ago47m ago
WebsiteVisit →Visit →

What is rmediation?

RMediation shipped a three-normal CDF, then found it was silently wrong.

RMediation is a long-standing CRAN package for confidence intervals on mediated effects, now built on an S7 class hierarchy. Over eight weeks it added ProductNormal3 for serial indirect effects of the form a1*a2*b, folded the engine into the existing pprodnormal naming family, and then replaced that engine outright after finding it returned wrong probabilities without warning. The dev branch is at 1.7.0; CRAN still serves 1.6.1.

Read the full rmediation trajectory →

What is scTypeEval?

scTypeEval judges single-cell annotations without needing a ground truth to judge them against.

scTypeEval evaluates the consistency of single-cell cell type annotations without a ground-truth reference, using pseudobulk distances, Wasserstein distances and reciprocal classification as alternative dissimilarity strategies. It cleared Bioconductor's submission process on its first cycle, moving from a 0.99.30 pre-release in April 2026 to version 1.0.0 in the Bioconductor 3.23 release a month later. It accepts matrix, Seurat and SingleCellExperiment inputs.

Read the full scTypeEval trajectory →

rmediation vs scTypeEval: editorial side-by-side

R
rmediation
ANALYTICS
3.8

RMediation shipped a three-normal CDF, then found it was silently wrong.

◆ Current state

RMediation is a long-standing CRAN package for confidence intervals on mediated effects, now built on an S7 class hierarchy. Over eight weeks it added ProductNormal3 for serial indirect effects of the form a1*a2*b, folded the engine into the existing pprodnormal naming family, and then replaced that engine outright after finding it returned wrong probabilities without warning. The dev branch is at 1.7.0; CRAN still serves 1.6.1.

◆ Where it's heading

The package is moving from a hand-rolled numerical layer to one that checks itself: the new default integrator escalates its node count until successive rules agree, warns when it hits the cap instead of returning a number, and exposes a diagnostics argument for the convergence estimate. The correctness fix went to dev ahead of the CRAN window rather than being held for it, which suggests wrong-answer bugs are treated as release-blocking regardless of cadence. Serial mediation is where the new surface area is concentrated.

◆ Prediction

1.7.0 exists specifically to land before CRAN's 2026-08-21 update window, so the next move is a CRAN submission promoting it to main; whether hcubature survives past that as a cross-check option is the open question.

S
scTypeEval
ANALYTICS
0.0

scTypeEval judges single-cell annotations without needing a ground truth to judge them against.

◆ Current state

scTypeEval evaluates the consistency of single-cell cell type annotations without a ground-truth reference, using pseudobulk distances, Wasserstein distances and reciprocal classification as alternative dissimilarity strategies. It cleared Bioconductor's submission process on its first cycle, moving from a 0.99.30 pre-release in April 2026 to version 1.0.0 in the Bioconductor 3.23 release a month later. It accepts matrix, Seurat and SingleCellExperiment inputs.

◆ Where it's heading

The visible history is short and shaped entirely by the Bioconductor pipeline — the 0.99.x series is that project's submission convention, and 1.0.0 is what acceptance looks like rather than a maturity claim by the authors. What the pre-release notes emphasise is breadth of input format and of dissimilarity strategy rather than a single recommended method, which suggests the package is positioned as a comparison harness rather than a scoring tool. Nothing in these two entries indicates work beyond getting accepted.

◆ Prediction

With only a submission cycle in the record, there is not enough here to predict a direction; the next release will most likely be whatever the Bioconductor 3.24 cycle requires, and the first post-acceptance release is what will show whether development continues.

Alternatives to rmediation and scTypeEval

Other Analytics products tracked by Sparkpulse, ranked by recent ship velocity. Each card links to a full editorial trajectory and lets you pivot into a head-to-head comparison with either rmediation or scTypeEval.

See all rmediation alternatives → · See all scTypeEval alternatives →

Recent activity from rmediation and scTypeEval

Latest ship moves from both products, interleaved chronologically. ⚡ = editorial spark.

  1. 8h agormediationv1.7.0 — pprodnormal3() correctness fix
  2. 1mo agormediationp_prod3() renamed into the pprodnormal family
  3. 1mo agormediationProductNormal3: exact CDF for a product of three normals
  4. 1mo agormediationmedfit reaches CRAN; Remotes pointer dropped
  5. 3mo agoscTypeEvalAccepted into the Bioconductor 3.23 release
  6. 4mo agoscTypeEvalBioconductor pre-release: ground-truth-agnostic annotation evaluation

Frequently asked questions

What is the difference between rmediation and scTypeEval?

Both compete on the same themes — r package — within Analytics. rmediation is currently shipping more aggressively (velocity 3.8 vs 0.0), with 1 editorial sparks in the last 30 days against 0. See the at-a-glance table above for a side-by-side breakdown of velocity, recent sparks, and editorial themes.

Is rmediation better than scTypeEval?

Sparkpulse doesn't pick a winner — we score release velocity, not feature parity. rmediation is currently shipping more aggressively (velocity 3.8 vs 0.0), with 1 editorial sparks in the last 30 days against 0. For your specific use case, the alternatives sections above list other Analytics products to evaluate alongside.

What are the best alternatives to rmediation?

Top rmediation alternatives in Analytics are ranked by recent ship velocity. Browse the "rmediation alternatives" section above for the current picks, or visit /alternatives/rmediation for the full list with editorial commentary on each.

What are the best alternatives to scTypeEval?

Top scTypeEval alternatives in Analytics are ranked by recent ship velocity. Browse the "scTypeEval alternatives" section above for the current picks, or visit /alternatives/sctypeeval for the full list with editorial commentary on each.