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Comparison · Analytics
regfusionr vs scTypeEval
A side-by-side editorial comparison of regfusionr and scTypeEval — release velocity, themes, recent moves, and the top alternatives to consider.
regfusionr vs scTypeEval: at a glance
What is regfusionr?
Registration fusion mapping goes bidirectional, and a vertex-indexing bug that silently returned wrong coordinates is fixed
regfusionr maps coordinates between volumetric brain templates (MNI152, Colin27) and the fsaverage surface. After four dormant years it returned in July 2026 with a release that fixes a coordinate-indexing bug, unblocks a previously disabled function, and completes the template-by-method matrix so all four combinations answer point queries. It also breaks compatibility by switching to the standard FREESURFER_HOME environment variable.
What is scTypeEval?
scTypeEval judges single-cell annotations without needing a ground truth to judge them against.
scTypeEval evaluates the consistency of single-cell cell type annotations without a ground-truth reference, using pseudobulk distances, Wasserstein distances and reciprocal classification as alternative dissimilarity strategies. It cleared Bioconductor's submission process on its first cycle, moving from a 0.99.30 pre-release in April 2026 to version 1.0.0 in the Bioconductor 3.23 release a month later. It accepts matrix, Seurat and SingleCellExperiment inputs.
regfusionr vs scTypeEval: editorial side-by-side
regfusionr
3.8ANALYTICS
Registration fusion mapping goes bidirectional, and a vertex-indexing bug that silently returned wrong coordinates is fixed
◆ Current state
regfusionr maps coordinates between volumetric brain templates (MNI152, Colin27) and the fsaverage surface. After four dormant years it returned in July 2026 with a release that fixes a coordinate-indexing bug, unblocks a previously disabled function, and completes the template-by-method matrix so all four combinations answer point queries. It also breaks compatibility by switching to the standard FREESURFER_HOME environment variable.
◆ Where it's heading
The package moved from a partial implementation to a complete one in a single release. Before this, vol_coords_to_fsaverage returned coordinates indexed by query position rather than by vertex index — results that looked plausible and were wrong — and fsaverage_to_vol was guarded behind a stop(). Both are now resolved, and the new Colin27 and MNI152 convenience functions make the mapping bidirectional. The sibling package haze shipped a maintenance release 56 minutes later, marking this as a coordinated sweep across the maintainer's neuroimaging stack.
◆ Prediction
With the four template-by-method combinations closed and the coordinate bug fixed, the next release is more likely to be CRAN-adjacent packaging or documentation than new mapping capability.
scTypeEval
0.0ANALYTICS
scTypeEval judges single-cell annotations without needing a ground truth to judge them against.
◆ Current state
scTypeEval evaluates the consistency of single-cell cell type annotations without a ground-truth reference, using pseudobulk distances, Wasserstein distances and reciprocal classification as alternative dissimilarity strategies. It cleared Bioconductor's submission process on its first cycle, moving from a 0.99.30 pre-release in April 2026 to version 1.0.0 in the Bioconductor 3.23 release a month later. It accepts matrix, Seurat and SingleCellExperiment inputs.
◆ Where it's heading
The visible history is short and shaped entirely by the Bioconductor pipeline — the 0.99.x series is that project's submission convention, and 1.0.0 is what acceptance looks like rather than a maturity claim by the authors. What the pre-release notes emphasise is breadth of input format and of dissimilarity strategy rather than a single recommended method, which suggests the package is positioned as a comparison harness rather than a scoring tool. Nothing in these two entries indicates work beyond getting accepted.
◆ Prediction
With only a submission cycle in the record, there is not enough here to predict a direction; the next release will most likely be whatever the Bioconductor 3.24 cycle requires, and the first post-acceptance release is what will show whether development continues.
Alternatives to regfusionr and scTypeEval
Other Analytics products tracked by Sparkpulse, ranked by recent ship velocity. Each card links to a full editorial trajectory and lets you pivot into a head-to-head comparison with either regfusionr or scTypeEval.
lstar
A single-cell data store commits to Zarr v3 and range-readable hosting across four language surfaces
quanteda
Text analysis in R keeps optimising its token internals — and builds a path out to torch
moderndive
The ModernDive teaching package learns to render inside the browser that runs its own textbook
glmbayes
A GPU-accelerated Bayesian GLM package buys its way into the standard R Bayesian toolchain
hydroloom
USGS puts a type system over its river network toolkit so errors surface at dispatch
See all regfusionr alternatives → · See all scTypeEval alternatives →
Recent activity from regfusionr and scTypeEval
Latest ship moves from both products, interleaved chronologically. ⚡ = editorial spark.
- 18d agoregfusionrVersion 0.3.0 -- vol_to_fsaverage, many convenience functions and fixes ⚡
- 3mo agoscTypeEvalAccepted into the Bioconductor 3.23 release
- 4mo agoscTypeEvalBioconductor pre-release: ground-truth-agnostic annotation evaluation
- 4y agoregfusionrv0.2.0 -- surface to volume data projection
- 4y agoregfusionrv0.1.0: Initial release
Frequently asked questions
What is the difference between regfusionr and scTypeEval?
They serve adjacent needs but don't currently overlap on shipped themes. regfusionr is currently shipping more aggressively (velocity 3.8 vs 0.0), with 1 editorial sparks in the last 30 days against 0. See the at-a-glance table above for a side-by-side breakdown of velocity, recent sparks, and editorial themes.
Is regfusionr better than scTypeEval?
Sparkpulse doesn't pick a winner — we score release velocity, not feature parity. regfusionr is currently shipping more aggressively (velocity 3.8 vs 0.0), with 1 editorial sparks in the last 30 days against 0. For your specific use case, the alternatives sections above list other Analytics products to evaluate alongside.
What are the best alternatives to regfusionr?
Top regfusionr alternatives in Analytics are ranked by recent ship velocity. Browse the "regfusionr alternatives" section above for the current picks, or visit /alternatives/regfusionr for the full list with editorial commentary on each.
What are the best alternatives to scTypeEval?
Top scTypeEval alternatives in Analytics are ranked by recent ship velocity. Browse the "scTypeEval alternatives" section above for the current picks, or visit /alternatives/sctypeeval for the full list with editorial commentary on each.