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Comparison · Analytics
qtl2fst vs tglkmeans
A side-by-side editorial comparison of qtl2fst and tglkmeans — release velocity, themes, recent moves, and the top alternatives to consider.
Shared themes:r-package
qtl2fst vs tglkmeans: at a glance
What is qtl2fst?
The out-of-memory backend for R/qtl2, feature-complete since 2020 and now purely on upkeep
qtl2fst backs R/qtl2 genotype probabilities with on-disk fst files so large crosses don't have to fit in RAM. Its defining release was 0.22 in 2020, which added calc_genoprob_fst() and genoprob_to_alleleprob_fst() to fuse calculation and storage in one step. The five releases since are documentation links, directory-creation robustness, a Windows example fix, and — in 0.32 — a change to how cores=0 is interpreted.
What is tglkmeans?
A k-means implementation that just told users their Spearman clustering on missing data was wrong
tglkmeans is a multi-core k-means implementation with seeding, aimed at single-cell and other large matrix workloads. Version 0.4.0 flipped the id_column default and moved to R's random number generator, 0.5.x added count-matrix downsampling and fixed id handling, and 0.6.3 in May 2026 is a correctness release: Spearman distance was ranking missing values as the largest value instead of dropping them, and predict_tgl_kmeans() with Euclidean distance did not reproduce the training metric when a cluster center had a missing dimension.
qtl2fst vs tglkmeans: editorial side-by-side
qtl2fst
0.0ANALYTICS
The out-of-memory backend for R/qtl2, feature-complete since 2020 and now purely on upkeep
◆ Current state
qtl2fst backs R/qtl2 genotype probabilities with on-disk fst files so large crosses don't have to fit in RAM. Its defining release was 0.22 in 2020, which added calc_genoprob_fst() and genoprob_to_alleleprob_fst() to fuse calculation and storage in one step. The five releases since are documentation links, directory-creation robustness, a Windows example fix, and — in 0.32 — a change to how cores=0 is interpreted.
◆ Where it's heading
The package has settled into the role of a stable satellite of R/qtl2: it tracks the parent package's conventions rather than setting its own. The cores=0 change in 0.32 arrived alongside the identical change in qtl2convert, so the parallel-computing default is being standardized across the maintainer's packages at once. Release intervals have stretched from months to years.
◆ Prediction
Further releases will most likely mirror changes originating in R/qtl2 or CRAN checks, in the same follow-the-parent pattern as 0.24 and 0.32.
tglkmeans
0.0ANALYTICS
A k-means implementation that just told users their Spearman clustering on missing data was wrong
◆ Current state
tglkmeans is a multi-core k-means implementation with seeding, aimed at single-cell and other large matrix workloads. Version 0.4.0 flipped the id_column default and moved to R's random number generator, 0.5.x added count-matrix downsampling and fixed id handling, and 0.6.3 in May 2026 is a correctness release: Spearman distance was ranking missing values as the largest value instead of dropping them, and predict_tgl_kmeans() with Euclidean distance did not reproduce the training metric when a cluster center had a missing dimension.
◆ Where it's heading
The package handles missing data across three distance metrics, and 0.6.3 shows those paths had drifted apart — Spearman behaved unlike Euclidean and Pearson, and prediction behaved unlike training. Both fixes change results on affected data, and the release notes are careful to bound exactly where: Spearman on data with NAs changes, complete data does not. Performance work runs alongside, with the dense per-thread vote matrix removed from the reassignment step.
◆ Prediction
With the metric paths now aligned on missing-value handling, further work is more likely to target the parallel reassignment internals than the distance semantics.
Alternatives to qtl2fst and tglkmeans
Other Analytics products tracked by Sparkpulse, ranked by recent ship velocity. Each card links to a full editorial trajectory and lets you pivot into a head-to-head comparison with either qtl2fst or tglkmeans.
gcube
gcube's recent releases are all packaging metadata, not simulation code
cubist
The R port of Quinlan's Cubist gets reproducibility fixes, not new modelling
ggstats
ggstats keeps widening what a coefficient or Likert plot can be
ecodive
ecodive rebuilt itself into a broad diversity-metric library, breaking as it went
simStateSpace
State-space data simulation for R, filled in one function at a time
See all qtl2fst alternatives → · See all tglkmeans alternatives →
Recent activity from qtl2fst and tglkmeans
Latest ship moves from both products, interleaved chronologically. ⚡ = editorial spark.
- 1mo agoqtl2fstcores=0 now leaves one core free instead of taking all
- 2mo agotglkmeansSpearman metric no longer ranks missing values as the largest
- 1y agoqtl2fstWindows fix for the replace_path() example
- 2y agoqtl2fstDocumentation link fix
- 2y agotglkmeansFixes corrupted cluster ids and dropped dimnames
- 2y agotglkmeansAdds downsample_matrix() for count matrices
- 2y agotglkmeansBreaking: id_column defaults to FALSE, switches to R's RNG
- 4y agoqtl2fstCreates missing directories instead of erroring out
- 5y agoqtl2fstTest coverage for qtl2 functions against fst-backed probabilities
- 6y agoqtl2fstDocumentation and metadata cleanup for CRAN
Frequently asked questions
What is the difference between qtl2fst and tglkmeans?
Both compete on the same themes — r-package — within Analytics. qtl2fst and tglkmeans are shipping at a similar cadence (velocity 0.0 vs 0.0, both within Sparkpulse's "active" band). See the at-a-glance table above for a side-by-side breakdown of velocity, recent sparks, and editorial themes.
Is qtl2fst better than tglkmeans?
Sparkpulse doesn't pick a winner — we score release velocity, not feature parity. qtl2fst and tglkmeans are shipping at a similar cadence (velocity 0.0 vs 0.0, both within Sparkpulse's "active" band). For your specific use case, the alternatives sections above list other Analytics products to evaluate alongside.
What are the best alternatives to qtl2fst?
Top qtl2fst alternatives in Analytics are ranked by recent ship velocity. Browse the "qtl2fst alternatives" section above for the current picks, or visit /alternatives/qtl2fst for the full list with editorial commentary on each.
What are the best alternatives to tglkmeans?
Top tglkmeans alternatives in Analytics are ranked by recent ship velocity. Browse the "tglkmeans alternatives" section above for the current picks, or visit /alternatives/tglkmeans for the full list with editorial commentary on each.