← Back to home
Comparison · Infra & APIs

PowerTOST vs valr

A side-by-side editorial comparison of PowerTOST and valr — release velocity, themes, recent moves, and the top alternatives to consider.

PowerTOST vs valr: at a glance

FeaturePowerTOSTvalr
SectorInfra & APIsInfra & APIs
Velocity score0.00.0
Sparks · 30d00
Top themesbioequivalence, sample-size, regulatory, pharmacometricsgenomics, interval-arithmetic, bioinformatics, bigwig
Last editorial update19h ago49m ago
WebsiteVisit →Visit →

What is PowerTOST?

A bioequivalence sample-size workhorse whose news is which regulator it now covers

PowerTOST computes power and sample size for bioequivalence and its changelog reads as a record of regulatory divergence more than statistical development. Version 1.5-3 added the Gulf Co-operation Council as a regulator setting; 1.5-4 and 1.5-6 stripped 'FDA' out of the narrow-therapeutic-index function names once China's CDE began requiring the same evaluation. The most recent release, 1.5-7, is a single fix to how nvec() splits a total sample size across sequences.

Read the full PowerTOST trajectory →

What is valr?

valr's interval verbs now read genomic files in place instead of demanding a loaded tibble.

valr reimplements bedtools-style genome interval arithmetic as tidyverse verbs backed by C++. Its long project has been closing the behavioural gap with bedtools — the book-ended interval semantics finally match in 0.10.0, three releases after the deprecation began. The July release also ends the assumption that intervals must be in memory: bed_map(), bed_intersect(), bed_subtract(), bed_coverage() and bed_window() accept a bigWig or bigBed path or URL where an interval table used to go.

Read the full valr trajectory →

PowerTOST vs valr: editorial side-by-side

P
PowerTOST
INFRA · APIS
0.0

A bioequivalence sample-size workhorse whose news is which regulator it now covers

◆ Current state

PowerTOST computes power and sample size for bioequivalence and its changelog reads as a record of regulatory divergence more than statistical development. Version 1.5-3 added the Gulf Co-operation Council as a regulator setting; 1.5-4 and 1.5-6 stripped 'FDA' out of the narrow-therapeutic-index function names once China's CDE began requiring the same evaluation. The most recent release, 1.5-7, is a single fix to how nvec() splits a total sample size across sequences.

◆ Where it's heading

The package is in long maintenance with a widening regulatory surface: the statistical methods are settled, and releases arrive when an agency publishes a framework that can be expressed as a settings variant of an existing method. Function naming has been deliberately decoupled from any single agency, with the deprecated FDA-suffixed aliases carried for years before removal. Cadence has slowed to roughly one release every eighteen months.

◆ Prediction

The next release is most likely another regulator setting or a small fix; on the deprecation notice already given, the power.NTIDFDA()-style aliases are the obvious removal candidate.

V
valr
INFRA · APIS
0.0

valr's interval verbs now read genomic files in place instead of demanding a loaded tibble.

◆ Current state

valr reimplements bedtools-style genome interval arithmetic as tidyverse verbs backed by C++. Its long project has been closing the behavioural gap with bedtools — the book-ended interval semantics finally match in 0.10.0, three releases after the deprecation began. The July release also ends the assumption that intervals must be in memory: bed_map(), bed_intersect(), bed_subtract(), bed_coverage() and bed_window() accept a bigWig or bigBed path or URL where an interval table used to go.

◆ Where it's heading

Two arcs converge here. One is compatibility: min_overlap arrived with a deprecation warning in 0.9.0 and its default flipped from 0 to 1 in 0.10.0, so book-ended intervals are excluded by default as bedtools does, with the internal calculations in bed_closest() and friends deliberately left counting them. The other is the file-backed path, which grew out of the cpp11bigwig dependency adopted in 0.8.3 for read_bigwig() and re-exported in 0.9.0 — reading a file became querying one. Underneath, the C++ base keeps getting lighter: Rcpp swapped for cpp11, rlang cut to a single function, per-group memory copies removed from three verbs.

◆ Prediction

Only five verbs take a file argument today and bed_closest(), bed_glyph() and the statistical verbs do not, so extending the file-backed path across the rest of the API is the obvious follow-up. The deprecated tibble re-exports and the now-defunct n_fields argument suggest continued removal of the compatibility layer in the next minor release.

Alternatives to PowerTOST and valr

Other Infra & APIs products tracked by Sparkpulse, ranked by recent ship velocity. Each card links to a full editorial trajectory and lets you pivot into a head-to-head comparison with either PowerTOST or valr.

See all PowerTOST alternatives → · See all valr alternatives →

Recent activity from PowerTOST and valr

Latest ship moves from both products, interleaved chronologically. ⚡ = editorial spark.

  1. 1mo agovalrInterval verbs read bigWig and bigBed files directly
  2. 7mo agovalrbed_slop() and bed_flank() preserve input row order
  3. 8mo agovalrmin_overlap introduced; C++ backend moves from Rcpp to cpp11
  4. 10mo agoPowerTOSTFix for splitting total sample size across sequences
  5. 1y agovalrTest updated for ggplot2 3.6.0
  6. 1y agovalrread_bigwig() switches to cpp11bigwig; read_gtf() deprecated
  7. 1y agovalrCRAN Rd link NOTE and maintainer email change
  8. 2y agoPowerTOSTNTID functions renamed off the FDA acronym; GCC guidance in vignettes
  9. 4y agoPowerTOSTpower.NTID() aliases added; FDA-suffixed names deprecated
  10. 5y agoPowerTOSTGulf Co-operation Council added as a regulator setting
  11. 5y agoPowerTOSTMaintenance release with vignette and documentation clarifications
  12. 5y agoPowerTOSTstringsAsFactors fix for older R in a vignette example

Frequently asked questions

What is the difference between PowerTOST and valr?

They serve adjacent needs but don't currently overlap on shipped themes. PowerTOST and valr are shipping at a similar cadence (velocity 0.0 vs 0.0, both within Sparkpulse's "active" band). See the at-a-glance table above for a side-by-side breakdown of velocity, recent sparks, and editorial themes.

Is PowerTOST better than valr?

Sparkpulse doesn't pick a winner — we score release velocity, not feature parity. PowerTOST and valr are shipping at a similar cadence (velocity 0.0 vs 0.0, both within Sparkpulse's "active" band). For your specific use case, the alternatives sections above list other Infra & APIs products to evaluate alongside.

What are the best alternatives to PowerTOST?

Top PowerTOST alternatives in Infra & APIs are ranked by recent ship velocity. Browse the "PowerTOST alternatives" section above for the current picks, or visit /alternatives/powertost for the full list with editorial commentary on each.

What are the best alternatives to valr?

Top valr alternatives in Infra & APIs are ranked by recent ship velocity. Browse the "valr alternatives" section above for the current picks, or visit /alternatives/valr for the full list with editorial commentary on each.