mice
mice can finally predict, not just estimate, from multiply imputed data.
A side-by-side editorial comparison of PEIMAN2 and plssem — release velocity, themes, recent moves, and the top alternatives to consider.
| Feature | PEIMAN2 | plssem |
|---|---|---|
| Sector | Infra & APIs | Infra & APIs |
| Velocity score | 0.0 | 0.0 |
| Sparks · 30d | 0 | 0 |
| Top themes | proteomics, post-translational-modification, enrichment-analysis, reproducibility | structural-equation-modeling, partial-least-squares, multilevel-models, standard-errors |
| Last editorial update | 2h ago | 2h ago |
| Website | Visit → | Visit → |
PEIMAN2 cut its annotation database loose from its release cycle without breaking CRAN.
PEIMAN2 does enrichment analysis over post-translational modifications, testing whether a protein list is enriched for particular PTMs against UniProt-derived annotations, with translation functions bridging to mass spectrometry workflows. Its answers are only as current as its bundled database, and until June that database could only be refreshed by releasing a new package version. Version 1.1.0 changes that.
plssem took PLS-SEM into multilevel data, then spent two releases making the estimates trustworthy.
plssem is a young R implementation of partial least squares structural equation modelling, three CRAN releases old and shipping monthly. Its distinguishing work is the MC-PLS family — consistent PLS estimators the maintainer extended to mixed-effects designs in June — and the releases since have been about getting standard errors, admissibility and fit measures onto the same footing as the point estimates.
PEIMAN2 does enrichment analysis over post-translational modifications, testing whether a protein list is enriched for particular PTMs against UniProt-derived annotations, with translation functions bridging to mass spectrometry workflows. Its answers are only as current as its bundled database, and until June that database could only be refreshed by releasing a new package version. Version 1.1.0 changes that.
The package has been moving from a fixed snapshot toward versioned, user-selectable data. Earlier releases updated the bundled database in place — 1.0.0 shipped the March 2025 version and said little else — which meant the annotation vintage was whatever the package version implied. Now update_peiman_database() downloads and caches external database files and UniProt PTM lists, enrichment workflows take a database_version argument, and the mass-spec translators take a ptmlist_version, so an analysis can pin a dated database rather than a package release. The CRAN-safe default is preserved deliberately: loading, examples and checks still use the bundled internal data and need no network.
Version pinning is now expressible but the release notes do not describe how a chosen version is recorded in output, so surfacing the active database version in results is the natural companion. The database and the UniProt PTM list are versioned separately, which leaves room for a combined manifest.
plssem is a young R implementation of partial least squares structural equation modelling, three CRAN releases old and shipping monthly. Its distinguishing work is the MC-PLS family — consistent PLS estimators the maintainer extended to mixed-effects designs in June — and the releases since have been about getting standard errors, admissibility and fit measures onto the same footing as the point estimates.
The pattern is capability first, inference second. Multilevel MC-PLSc and MC-OrdPLSc arrived in 0.1.2 together with Monte-Carlo delta-method standard errors and a Polyak-Juditsky extrapolation step; 0.1.3 then extended delta-method errors to redundant parameters and thresholds, optimized their computation, added a loglikelihood-based fit measure and generated dynamic bounds to keep MC-PLS solutions admissible. Admissibility recurs throughout — penalized inadmissible solutions in 0.1.1, variance lower bounds and negative residual variance handling in 0.1.3, and an option to drop inadmissible bootstraps rather than silently include them. The release notes are pull-request lists, so the reasoning behind each change stays in the repository.
The MIMIC mode and GLS estimator both landed in the most recent release without the standard-error and fit-measure work that followed earlier additions, so extending inference to cover them is the natural next step. Bootstrap defaults moving to 500 replications suggests runtime is a live constraint and further optimization is likely.
Other Infra & APIs products tracked by Sparkpulse, ranked by recent ship velocity. Each card links to a full editorial trajectory and lets you pivot into a head-to-head comparison with either PEIMAN2 or plssem.
mice can finally predict, not just estimate, from multiply imputed data.
A market-microstructure toolkit that keeps adding estimators as the papers land.
A vowel-analysis package trimming dependencies after an email address got it archived.
The R half of the EMU speech database system, fixing what was quietly broken.
A Bayesian model-averaging package spending its 2.0 on memory, not methods.
tidyplots keeps rebuilding its own foundations rather than layering around them.
See all PEIMAN2 alternatives → · See all plssem alternatives →
Latest ship moves from both products, interleaved chronologically. ⚡ = editorial spark.
Both compete on the same themes — r-packages — within Infra & APIs. PEIMAN2 and plssem are shipping at a similar cadence (velocity 0.0 vs 0.0, both within Sparkpulse's "active" band). See the at-a-glance table above for a side-by-side breakdown of velocity, recent sparks, and editorial themes.
Sparkpulse doesn't pick a winner — we score release velocity, not feature parity. PEIMAN2 and plssem are shipping at a similar cadence (velocity 0.0 vs 0.0, both within Sparkpulse's "active" band). For your specific use case, the alternatives sections above list other Infra & APIs products to evaluate alongside.
Top PEIMAN2 alternatives in Infra & APIs are ranked by recent ship velocity. Browse the "PEIMAN2 alternatives" section above for the current picks, or visit /alternatives/peiman2 for the full list with editorial commentary on each.
Top plssem alternatives in Infra & APIs are ranked by recent ship velocity. Browse the "plssem alternatives" section above for the current picks, or visit /alternatives/plssem for the full list with editorial commentary on each.