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gsDesign2 vs r2rtf

A side-by-side editorial comparison of gsDesign2 and r2rtf — release velocity, themes, recent moves, and the top alternatives to consider.

Shared themes:pharmaverse

gsDesign2 vs r2rtf: at a glance

FeaturegsDesign2r2rtf
SectorAnalyticsAnalytics
Velocity score3.80.0
Sparks · 30d10
Top themesclinical-trials, group-sequential, biostatistics, pharmaverseclinical-reporting, rtf, internationalization, document-conversion
Last editorial update3h ago1h ago
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What is gsDesign2?

Group sequential design tooling that now monitors for harm, not just efficacy and futility.

gsDesign2 is the Merck-authored R package for group sequential clinical trial design under non-proportional hazards, and it has spent the last two years filling in the statistical surface its predecessor gsDesign established. Recent releases added conditional power (gs_cp, gs_cp_npe), sequential p-values, risk-difference designs with minimal risk weighting, and boundary updates from blinded interim estimates. Version 1.2.0 adds harm boundaries across the AHR and NPE design and power functions, wired through every summary and table export path.

Read the full gsDesign2 trajectory →

What is r2rtf?

The clinical-report table engine learned Chinese, then learned to leave RTF entirely

r2rtf builds the RTF tables, listings and figures that go into clinical study reports, and its recent releases have been about widening who and what it can serve rather than changing how tables are composed. The 1.2.0 release added internationalization — a SimSun font path for Chinese characters plus hyphenation control — and 1.3.0 followed with write_docx() and write_html(), turning the LibreOffice conversion the package had documented into exported functions.

Read the full r2rtf trajectory →

gsDesign2 vs r2rtf: editorial side-by-side

G
gsDesign2
ANALYTICS
3.8

Group sequential design tooling that now monitors for harm, not just efficacy and futility.

◆ Current state

gsDesign2 is the Merck-authored R package for group sequential clinical trial design under non-proportional hazards, and it has spent the last two years filling in the statistical surface its predecessor gsDesign established. Recent releases added conditional power (gs_cp, gs_cp_npe), sequential p-values, risk-difference designs with minimal risk weighting, and boundary updates from blinded interim estimates. Version 1.2.0 adds harm boundaries across the AHR and NPE design and power functions, wired through every summary and table export path.

◆ Where it's heading

The package is converging on parity with gsDesign while extending past it — each release either closes a gap against the older package or adds a boundary type gsDesign never had. A visible second track is output plumbing: every new statistical feature now arrives already threaded through summary(), gs_bound_summary(), as_gt(), and as_rtf(), which is what regulatory submission work actually consumes. Performance work is steady but secondary, with gs_design_ahr() roughly 2x faster in 1.1.9.

◆ Prediction

Expect the harm boundary work to propagate into the WLR and risk-difference design families, which are the two design branches 1.2.0 left untouched, along with a vignette bridging harm boundaries to the remaining gsDesign test types.

R
r2rtf
ANALYTICS
0.0

The clinical-report table engine learned Chinese, then learned to leave RTF entirely

◆ Current state

r2rtf builds the RTF tables, listings and figures that go into clinical study reports, and its recent releases have been about widening who and what it can serve rather than changing how tables are composed. The 1.2.0 release added internationalization — a SimSun font path for Chinese characters plus hyphenation control — and 1.3.0 followed with write_docx() and write_html(), turning the LibreOffice conversion the package had documented into exported functions.

◆ Where it's heading

Two threads run through the window. One is output reach: RTF remains the composition target, but the artifacts that come out of it now include DOCX and HTML, and page numbering can be made table-relative across multi-page tables. The other is durability under a moving R and font stack — the ANSI/Unicode converter was rebuilt, the LaTeX mapping table generated from code rather than shipped as sysdata, unlist() usage fixed for R 4.5, and graphics-device leaks that produced stray Rplots.pdf closed off.

◆ Prediction

Having exported DOCX and HTML conversion, the likely next step is filling in what those formats lose relative to RTF — pagination and footnote fidelity are the obvious gaps. The i18n path currently covers Chinese only, so additional font families are the other plausible direction.

Alternatives to gsDesign2 and r2rtf

Other Analytics products tracked by Sparkpulse, ranked by recent ship velocity. Each card links to a full editorial trajectory and lets you pivot into a head-to-head comparison with either gsDesign2 or r2rtf.

See all gsDesign2 alternatives → · See all r2rtf alternatives →

Recent activity from gsDesign2 and r2rtf

Latest ship moves from both products, interleaved chronologically. ⚡ = editorial spark.

  1. 9d agogsDesign2Harm boundaries land in AHR and NPE group sequential designs
  2. 1mo agogsDesign2Conditional power, sequential p-values, and minimal risk weighting
  3. 5mo agogsDesign2gs_design_ahr() can output spending time
  4. 7mo agor2rtfDOCX and HTML output become exported functions
  5. 8mo agogsDesign2S3 class refactor and futility boundary vignette
  6. 11mo agogsDesign2h1_spending for WLR power, info_scale across fixed designs
  7. 11mo agor2rtfChinese character support arrives via an i18n font path
  8. 1y agogsDesign2WLR design spending default corrected to information fraction
  9. 1y agor2rtfText colour fixed for figures encoded into RTF
  10. 1y agor2rtfFootnote handling fixed for R 4.5.0
  11. 1y agor2rtfUnicode converter rebuilt and mapping table made inspectable
  12. 2y agor2rtfUTF-8 conversion fix and LibreOffice 7.6 support

Frequently asked questions

What is the difference between gsDesign2 and r2rtf?

Both compete on the same themes — pharmaverse — within Analytics. gsDesign2 is currently shipping more aggressively (velocity 3.8 vs 0.0), with 1 editorial sparks in the last 30 days against 0. See the at-a-glance table above for a side-by-side breakdown of velocity, recent sparks, and editorial themes.

Is gsDesign2 better than r2rtf?

Sparkpulse doesn't pick a winner — we score release velocity, not feature parity. gsDesign2 is currently shipping more aggressively (velocity 3.8 vs 0.0), with 1 editorial sparks in the last 30 days against 0. For your specific use case, the alternatives sections above list other Analytics products to evaluate alongside.

What are the best alternatives to gsDesign2?

Top gsDesign2 alternatives in Analytics are ranked by recent ship velocity. Browse the "gsDesign2 alternatives" section above for the current picks, or visit /alternatives/gsdesign2 for the full list with editorial commentary on each.

What are the best alternatives to r2rtf?

Top r2rtf alternatives in Analytics are ranked by recent ship velocity. Browse the "r2rtf alternatives" section above for the current picks, or visit /alternatives/r2rtf for the full list with editorial commentary on each.