STACAS
Single-cell batch correction that learned to use cell labels, then spent three releases chasing Seurat.
Comparison · Analytics
GeneNMF vs sdsfun
A side-by-side editorial comparison of GeneNMF and sdsfun — release velocity, themes, recent moves, and the top alternatives to consider.
Shared themes:r-package
GeneNMF vs sdsfun: at a glance
What is GeneNMF?
GeneNMF rebuilt how it derives meta-programs, changing every result it had produced.
GeneNMF applies non-negative matrix factorization to single-cell expression data to find gene programs, then consolidates programs recurring across samples into meta-programs. Version 0.6.0 replaced the consolidation method: instead of reducing each program to a gene set and taking a consensus, it retains full gene weight vectors and compares them by cosine similarity. Later releases have built reporting and control around that core — a metaprogram composition matrix showing which samples contributed, custom signature databases for enrichment testing, and the ability to drop meta-programs from results.
What is sdsfun?
A spatial-statistics utility package exists to be depended on, and is built accordingly.
sdsfun collects spatial data science utilities — neighbour lists, spatial constrained clustering, discretization, dummy variable generation, geographical detector statistics and projection helpers — with the computationally heavy parts implemented in Rcpp. It was assembled quickly across late 2024, adding a function set roughly every three weeks, and has slowed since to a couple of releases a year. The most recent work is corrective: no longer initializing the RNG state at load, fixing matrix inputs misread as vectors, and clearing an Armadillo deprecation.
GeneNMF vs sdsfun: editorial side-by-side
GeneNMF
0.0ANALYTICS
GeneNMF rebuilt how it derives meta-programs, changing every result it had produced.
◆ Current state
GeneNMF applies non-negative matrix factorization to single-cell expression data to find gene programs, then consolidates programs recurring across samples into meta-programs. Version 0.6.0 replaced the consolidation method: instead of reducing each program to a gene set and taking a consensus, it retains full gene weight vectors and compares them by cosine similarity. Later releases have built reporting and control around that core — a metaprogram composition matrix showing which samples contributed, custom signature databases for enrichment testing, and the ability to drop meta-programs from results.
◆ Where it's heading
The package is moving from producing meta-programs to letting users interrogate and constrain how they were formed. Composition matrices, the drop function and downsampled similarity heatmaps all serve inspection rather than derivation. The parameters added alongside the 0.6.0 rewrite — specificity weighting, cumulative weight thresholds, confidence defined as the fraction of programs containing a gene — turn what were fixed internal choices into stated, tunable ones.
◆ Prediction
Recent releases have been fixes and compatibility work rather than method changes, so the core approach appears settled. The dependency on an RcppML version not on CRAN is the loose end most likely to force the next release.
sdsfun
0.0ANALYTICS
A spatial-statistics utility package exists to be depended on, and is built accordingly.
◆ Current state
sdsfun collects spatial data science utilities — neighbour lists, spatial constrained clustering, discretization, dummy variable generation, geographical detector statistics and projection helpers — with the computationally heavy parts implemented in Rcpp. It was assembled quickly across late 2024, adding a function set roughly every three weeks, and has slowed since to a couple of releases a year. The most recent work is corrective: no longer initializing the RNG state at load, fixing matrix inputs misread as vectors, and clearing an Armadillo deprecation.
◆ Where it's heading
This is infrastructure for a family of packages rather than an end-user tool, and the changelog says so directly — functions were added to support gdverse and sesp, and moran_test was migrated in from geocomplexity. That migration pattern is the defining move: capability consolidates here so the downstream packages can share it instead of each carrying its own copy. Growth has slowed as that consolidation completed, leaving correctness and dependency upkeep.
◆ Prediction
Given the package moves when its dependents need something, the next release most likely brings in another shared function or responds to a downstream requirement rather than following its own plan. Armadillo and CRAN check changes remain the reliable source of maintenance work.
Alternatives to GeneNMF and sdsfun
Other Analytics products tracked by Sparkpulse, ranked by recent ship velocity. Each card links to a full editorial trajectory and lets you pivot into a head-to-head comparison with either GeneNMF or sdsfun.
ggtrace
A debugger for ggplot2's internals, hardening its grip as the internals it traces keep moving.
kde1d
A univariate density estimator that added zero-inflated data and reopened its C++ API to do it.
svines
Stationary vine copulas for time series, released in lockstep with the rest of Nagler's vine stack.
gghighlight
A single-purpose ggplot2 extension that has spent six years tracking ggplot2 instead of growing.
rtrek
A Star Trek data package that became a Memory Alpha web client and has been patching scrapers ever since.
See all GeneNMF alternatives → · See all sdsfun alternatives →
Recent activity from GeneNMF and sdsfun
Latest ship moves from both products, interleaved chronologically. ⚡ = editorial spark.
- 10mo agosdsfunPackage load stops touching the RNG state
- 11mo agoGeneNMFSingle-sample runs fixed; gene weight definition refined
- 1y agosdsfunUnified partial correlation testing and head/tails discretization
- 1y agoGeneNMFMetaprogram composition exposed and custom signature DBs supported
- 1y agosdsfunMissing-value handling added to linear trend removal
- 1y agosdsfunCovariate-based detrending and long-to-matrix spatial reshaping
- 1y agosdsfunSpatially constrained hierarchical clustering and SPADE estimation
- 1y agoGeneNMFSimilarity heatmap downsampling and meta-program removal
- 1y agosdsfunFast geodetector q-value estimator added
- 2y agoGeneNMFMeta-programs rebuilt on gene weight vectors and cosine similarity ⚡
- 2y agoGeneNMFFirst stable release published to CRAN
Frequently asked questions
What is the difference between GeneNMF and sdsfun?
Both compete on the same themes — r-package — within Analytics. GeneNMF and sdsfun are shipping at a similar cadence (velocity 0.0 vs 0.0, both within Sparkpulse's "active" band). See the at-a-glance table above for a side-by-side breakdown of velocity, recent sparks, and editorial themes.
Is GeneNMF better than sdsfun?
Sparkpulse doesn't pick a winner — we score release velocity, not feature parity. GeneNMF and sdsfun are shipping at a similar cadence (velocity 0.0 vs 0.0, both within Sparkpulse's "active" band). For your specific use case, the alternatives sections above list other Analytics products to evaluate alongside.
What are the best alternatives to GeneNMF?
Top GeneNMF alternatives in Analytics are ranked by recent ship velocity. Browse the "GeneNMF alternatives" section above for the current picks, or visit /alternatives/genenmf for the full list with editorial commentary on each.
What are the best alternatives to sdsfun?
Top sdsfun alternatives in Analytics are ranked by recent ship velocity. Browse the "sdsfun alternatives" section above for the current picks, or visit /alternatives/sdsfun for the full list with editorial commentary on each.