tidytlg
A tables-listings-graphs package that reached CRAN and then went quiet.
Comparison · Analytics
DoseFinding vs mirai
A side-by-side editorial comparison of DoseFinding and mirai — release velocity, themes, recent moves, and the top alternatives to consider.
DoseFinding vs mirai: at a glance
What is DoseFinding?
New stewardship at openpharma, then two releases adding the methods MCP-Mod was missing
DoseFinding implements MCP-Mod and related dose-response methodology for clinical trial design and analysis. In 2024 it changed hands — Marius Thomas took over as maintainer, Novartis was recorded as copyright holder and funder, and the package moved to the openpharma GitHub organisation with roxygen documentation and a proper NEWS file. The two releases since have added substantive methodology: model averaging for dose-response fitting in 1.3-1, and conditional and predictive power for interim analyses in 1.4-1.
What is mirai?
mirai removed its dispatcher process and added memory backpressure to the queue.
The async evaluation framework releases roughly monthly and moves fast at the architecture level. In 2.7.0 the dispatcher stopped being a separate process and became a thread, after its loop had already been rewritten in C inside nanonext one release earlier. The same release added an opt-in memory budget for queued task payloads and try_mirai(), which returns NULL immediately rather than blocking when that budget is exhausted.
DoseFinding vs mirai: editorial side-by-side
DoseFinding
0.0ANALYTICS
New stewardship at openpharma, then two releases adding the methods MCP-Mod was missing
◆ Current state
DoseFinding implements MCP-Mod and related dose-response methodology for clinical trial design and analysis. In 2024 it changed hands — Marius Thomas took over as maintainer, Novartis was recorded as copyright holder and funder, and the package moved to the openpharma GitHub organisation with roxygen documentation and a proper NEWS file. The two releases since have added substantive methodology: model averaging for dose-response fitting in 1.3-1, and conditional and predictive power for interim analyses in 1.4-1.
◆ Where it's heading
The pattern before the handover was maintenance — R-devel compliance, a bug fix, a link. After it, each release carries a named methodological addition with an acknowledged contributor, plus documentation to match: a longitudinal analysis vignette shipped alongside the interim power work. Housekeeping continues underneath, mostly clearing deprecated ggplot2 interfaces, aes_string in one release and qplot in the next.
◆ Prediction
Given the last two releases each added one method with a supporting vignette, expect the next to follow the same shape. Both additions so far extend the package beyond fixed dose-response fitting, so adaptive and interim methodology is the more likely direction.
mirai
2.5ANALYTICS
mirai removed its dispatcher process and added memory backpressure to the queue.
◆ Current state
The async evaluation framework releases roughly monthly and moves fast at the architecture level. In 2.7.0 the dispatcher stopped being a separate process and became a thread, after its loop had already been rewritten in C inside nanonext one release earlier. The same release added an opt-in memory budget for queued task payloads and try_mirai(), which returns NULL immediately rather than blocking when that budget is exhausted.
◆ Where it's heading
Two threads of work run together: cutting overhead out of the task path — thread-based dispatcher, in-process transport for synchronous daemons, lower per-element dispatch cost in mirai_map() — and making the framework safe to embed in an event loop, where blocking the host R thread is not acceptable. Deployment reach is growing too, with http_config() launching remote daemons over HTTP APIs and auto-configuring for Posit Workbench. Each release pins a minimum nanonext version, so the two packages advance as one unit.
◆ Prediction
With backpressure in place but opt-in, the open question these notes leave is whether a default memory budget arrives; continued overhead reduction and Shiny-facing non-blocking paths are the safer bet.
Alternatives to DoseFinding and mirai
Other Analytics products tracked by Sparkpulse, ranked by recent ship velocity. Each card links to a full editorial trajectory and lets you pivot into a head-to-head comparison with either DoseFinding or mirai.
Tplyr
Tplyr made clinical summary tables explain where every number came from.
rlistings
Clinical listings that keep inheriting their hardest problem — pagination — from the layer below.
hoardr
A cache-directory helper that has shipped nothing but CRAN-triggered patches for seven years.
gigs
gigs redesigned its whole conversion API for rOpenSci, then spent three releases getting the docs to build.
riem
A weather-data client that keeps rewriting its HTTP layer while slowly tightening its API.
See all DoseFinding alternatives → · See all mirai alternatives →
Recent activity from DoseFinding and mirai
Latest ship moves from both products, interleaved chronologically. ⚡ = editorial spark.
- 25d agomiraiMap collection and daemon lifecycle fixes
- 2mo agomiraiAgent skill ships in-package; HTTP headers take over auth
- 3mo agomiraiDispatcher becomes a thread, and the queue gains a memory budget ⚡
- 5mo agomiraiParallel RNG seeding leaves experimental status
- 6mo agomiraiRemote daemons over HTTP, and a C dispatcher loop
- 8mo agomiraiTelemetry span timing and daemon-switch fix
- 1y agoDoseFindingConditional and predictive power for interim analyses
- 1y agoDoseFindingModel averaging arrives for dose-response fitting ⚡
- 1y agoDoseFindingPackage moves to openpharma under new maintainership
- 2y agoDoseFindingCompliance update for R-devel
- 3y agoDoseFindingpowMCTBinCount bug fix
Frequently asked questions
What is the difference between DoseFinding and mirai?
They serve adjacent needs but don't currently overlap on shipped themes. mirai is currently shipping more aggressively (velocity 2.5 vs 0.0), with 0 editorial sparks in the last 30 days against 0. See the at-a-glance table above for a side-by-side breakdown of velocity, recent sparks, and editorial themes.
Is DoseFinding better than mirai?
Sparkpulse doesn't pick a winner — we score release velocity, not feature parity. mirai is currently shipping more aggressively (velocity 2.5 vs 0.0), with 0 editorial sparks in the last 30 days against 0. For your specific use case, the alternatives sections above list other Analytics products to evaluate alongside.
What are the best alternatives to DoseFinding?
Top DoseFinding alternatives in Analytics are ranked by recent ship velocity. Browse the "DoseFinding alternatives" section above for the current picks, or visit /alternatives/dosefinding for the full list with editorial commentary on each.
What are the best alternatives to mirai?
Top mirai alternatives in Analytics are ranked by recent ship velocity. Browse the "mirai alternatives" section above for the current picks, or visit /alternatives/mirai for the full list with editorial commentary on each.