tidytlg
A tables-listings-graphs package that reached CRAN and then went quiet.
Comparison · Analytics
DoseFinding vs metatools
A side-by-side editorial comparison of DoseFinding and metatools — release velocity, themes, recent moves, and the top alternatives to consider.
Shared themes:clinical-trials
DoseFinding vs metatools: at a glance
What is DoseFinding?
New stewardship at openpharma, then two releases adding the methods MCP-Mod was missing
DoseFinding implements MCP-Mod and related dose-response methodology for clinical trial design and analysis. In 2024 it changed hands — Marius Thomas took over as maintainer, Novartis was recorded as copyright holder and funder, and the package moved to the openpharma GitHub organisation with roxygen documentation and a proper NEWS file. The two releases since have added substantive methodology: model averaging for dose-response fitting in 1.3-1, and conditional and predictive power for interim analyses in 1.4-1.
What is metatools?
SDTM supplemental-qualifier merging got sturdier, then the package went quiet for two years.
metatools provides the utilities that build and check SDTM and ADaM datasets against their metadata in the pharmaverse. The 0.1.6 release in July 2024 is the substantive one: combine_supp() learned to handle zero-row supplemental data, to refuse QNAM columns already present in the source, and to route multiple QNAM values to the same IDVAR, alongside enhanced controlled-terminology checks and record-uniqueness verification. Nothing has shipped since.
DoseFinding vs metatools: editorial side-by-side
DoseFinding
0.0ANALYTICS
New stewardship at openpharma, then two releases adding the methods MCP-Mod was missing
◆ Current state
DoseFinding implements MCP-Mod and related dose-response methodology for clinical trial design and analysis. In 2024 it changed hands — Marius Thomas took over as maintainer, Novartis was recorded as copyright holder and funder, and the package moved to the openpharma GitHub organisation with roxygen documentation and a proper NEWS file. The two releases since have added substantive methodology: model averaging for dose-response fitting in 1.3-1, and conditional and predictive power for interim analyses in 1.4-1.
◆ Where it's heading
The pattern before the handover was maintenance — R-devel compliance, a bug fix, a link. After it, each release carries a named methodological addition with an acknowledged contributor, plus documentation to match: a longitudinal analysis vignette shipped alongside the interim power work. Housekeeping continues underneath, mostly clearing deprecated ggplot2 interfaces, aes_string in one release and qplot in the next.
◆ Prediction
Given the last two releases each added one method with a supporting vignette, expect the next to follow the same shape. Both additions so far extend the package beyond fixed dose-response fitting, so adaptive and interim methodology is the more likely direction.
metatools
0.0ANALYTICS
SDTM supplemental-qualifier merging got sturdier, then the package went quiet for two years.
◆ Current state
metatools provides the utilities that build and check SDTM and ADaM datasets against their metadata in the pharmaverse. The 0.1.6 release in July 2024 is the substantive one: combine_supp() learned to handle zero-row supplemental data, to refuse QNAM columns already present in the source, and to route multiple QNAM values to the same IDVAR, alongside enhanced controlled-terminology checks and record-uniqueness verification. Nothing has shipped since.
◆ Where it's heading
The package's development has been concentrated on one function, combine_supp(), which is where the messy realities of supplemental qualifiers surface — whitespace in join keys, empty supp datasets, colliding names. 0.1.6 also drew three first-time contributors, which is the healthiest signal in the history, but no release has followed. Sibling packages have meanwhile been dropping metatools as a dependency.
◆ Prediction
Without a release in two years the package looks stable rather than active; the plausible trigger is a controlled-terminology or dplyr change that forces the checks to be updated.
Alternatives to DoseFinding and metatools
Other Analytics products tracked by Sparkpulse, ranked by recent ship velocity. Each card links to a full editorial trajectory and lets you pivot into a head-to-head comparison with either DoseFinding or metatools.
Tplyr
Tplyr made clinical summary tables explain where every number came from.
rlistings
Clinical listings that keep inheriting their hardest problem — pagination — from the layer below.
hoardr
A cache-directory helper that has shipped nothing but CRAN-triggered patches for seven years.
gigs
gigs redesigned its whole conversion API for rOpenSci, then spent three releases getting the docs to build.
riem
A weather-data client that keeps rewriting its HTTP layer while slowly tightening its API.
See all DoseFinding alternatives → · See all metatools alternatives →
Recent activity from DoseFinding and metatools
Latest ship moves from both products, interleaved chronologically. ⚡ = editorial spark.
- 1y agoDoseFindingConditional and predictive power for interim analyses
- 1y agoDoseFindingModel averaging arrives for dose-response fitting ⚡
- 1y agoDoseFindingPackage moves to openpharma under new maintainership
- 2y agometatoolscombine_supp() hardened; controlled-terminology checks extended
- 2y agoDoseFindingCompliance update for R-devel
- 3y agoDoseFindingpowMCTBinCount bug fix
- 3y agometatools0.1.4 Update to dplyr and small bug fixes
- 4y agometatools0.1.1 first CRAN release
Frequently asked questions
What is the difference between DoseFinding and metatools?
Both compete on the same themes — clinical-trials — within Analytics. DoseFinding and metatools are shipping at a similar cadence (velocity 0.0 vs 0.0, both within Sparkpulse's "active" band). See the at-a-glance table above for a side-by-side breakdown of velocity, recent sparks, and editorial themes.
Is DoseFinding better than metatools?
Sparkpulse doesn't pick a winner — we score release velocity, not feature parity. DoseFinding and metatools are shipping at a similar cadence (velocity 0.0 vs 0.0, both within Sparkpulse's "active" band). For your specific use case, the alternatives sections above list other Analytics products to evaluate alongside.
What are the best alternatives to DoseFinding?
Top DoseFinding alternatives in Analytics are ranked by recent ship velocity. Browse the "DoseFinding alternatives" section above for the current picks, or visit /alternatives/dosefinding for the full list with editorial commentary on each.
What are the best alternatives to metatools?
Top metatools alternatives in Analytics are ranked by recent ship velocity. Browse the "metatools alternatives" section above for the current picks, or visit /alternatives/metatools for the full list with editorial commentary on each.