cIRT
A choice-based IRT model published once in 2019 and kept compiling ever since
Comparison · Analytics
DHARMa vs MetaboAnalystR
A side-by-side editorial comparison of DHARMa and MetaboAnalystR — release velocity, themes, recent moves, and the top alternatives to consider.
Shared themes:r-package
DHARMa vs MetaboAnalystR: at a glance
What is DHARMa?
DHARMa changed how GLMM residuals are simulated, so the same code now returns different numbers.
DHARMa generates scaled quantile residuals for fitted GLMMs and runs the dispersion, uniformity, and autocorrelation tests built on them. Version 0.5.0 changed the default simulation for hierarchical models from the model's own default, mostly unconditional, to conditional simulation, and states plainly that residuals will differ from those computed by older versions. The same release added brms to the supported model set and reworked how predictors are passed to plotting and testing functions.
What is MetaboAnalystR?
The R engine behind MetaboAnalyst closes the gap from raw spectra to biological interpretation
MetaboAnalystR is the scriptable form of the MetaboAnalyst web platform, carrying several hundred functions for metabolomics data analysis, visualisation and functional interpretation. Its releases have steadily pushed the starting line further upstream: version 1 assumed processed data, version 2 added raw LC-MS spectral processing, and the 4.x line presents the whole path from raw spectra through compound identification to functional interpretation as one workflow. It also now claims exposomics alongside metabolomics as an application area.
DHARMa vs MetaboAnalystR: editorial side-by-side
DHARMa
0.0ANALYTICS
DHARMa changed how GLMM residuals are simulated, so the same code now returns different numbers.
◆ Current state
DHARMa generates scaled quantile residuals for fitted GLMMs and runs the dispersion, uniformity, and autocorrelation tests built on them. Version 0.5.0 changed the default simulation for hierarchical models from the model's own default, mostly unconditional, to conditional simulation, and states plainly that residuals will differ from those computed by older versions. The same release added brms to the supported model set and reworked how predictors are passed to plotting and testing functions.
◆ Where it's heading
The package has spent several releases widening which model backends it can diagnose, from glmmTMB through mgcv, phylolm and now brms, while methodological work has gone into handling correlated residuals via the rotation argument. Version 0.5.0 shifts from adding coverage to changing defaults for statistical power. The formula interface arriving across plotResiduals, testCategorical, testQuantiles and the autocorrelation tests suggests the API is being unified rather than extended function by function.
◆ Prediction
The next releases will likely broaden brms support past the simple-model restriction and continue converting remaining functions to the formula interface.
MetaboAnalystR
0.0ANALYTICS
The R engine behind MetaboAnalyst closes the gap from raw spectra to biological interpretation
◆ Current state
MetaboAnalystR is the scriptable form of the MetaboAnalyst web platform, carrying several hundred functions for metabolomics data analysis, visualisation and functional interpretation. Its releases have steadily pushed the starting line further upstream: version 1 assumed processed data, version 2 added raw LC-MS spectral processing, and the 4.x line presents the whole path from raw spectra through compound identification to functional interpretation as one workflow. It also now claims exposomics alongside metabolomics as an application area.
◆ Where it's heading
The consistent move is absorbing steps that users previously stitched together from separate tools. Peak picking, alignment and annotation came in with 2.0; automated feature detection optimisation and compound identification came with the 4.x work. The releases are infrequent and paper-shaped — each major version is announced with publication text rather than a change list — which makes the version history read as a sequence of methods papers more than a software cadence.
◆ Prediction
The exposomics framing is the newest element and the least built out in these entries, which makes it the most likely direction for the next round of work.
Alternatives to DHARMa and MetaboAnalystR
Other Analytics products tracked by Sparkpulse, ranked by recent ship velocity. Each card links to a full editorial trajectory and lets you pivot into a head-to-head comparison with either DHARMa or MetaboAnalystR.
fmtr
Rebuilding SAS's formatting layer in R, one format specification at a time
betaselectr
Standardised coefficients for models where standardising everything is wrong — but the feed only links out
SSN2
Stream-network spatial models learning to run on data that no longer fits in memory
BiocManager
Bioconductor's installer, frozen at 1.30.x and tuned almost entirely through environment variables
dcurves
Decision curve analysis, settled since 2022 and now moving only when its neighbours do
See all DHARMa alternatives → · See all MetaboAnalystR alternatives →
Recent activity from DHARMa and MetaboAnalystR
Latest ship moves from both products, interleaved chronologically. ⚡ = editorial spark.
- 2mo agoDHARMaConditional simulation becomes the GLMM default, changing residuals ⚡
- 10mo agoMetaboAnalystRMetaboAnalystR 4.2: a unified LC-MS/MS workflow for global metabolomics and exposomics ⚡
- 1y agoDHARMaDHARMa 0.4.7
- 3y agoMetaboAnalystRMetaboAnalystR 3.3: Pre-version of version 4.0
- 3y agoDHARMaDHARMa 0.4.6
- 4y agoDHARMaDHARMa 0.4.5
- 4y agoDHARMaDHARMa 0.4.4
- 5y agoDHARMaDHARMa 0.4.3
- 7y agoMetaboAnalystRMetaboAnalystR 2.0: From Raw Spectra to Biological Insights
- 8y agoMetaboAnalystRInteractive 3D ordination plots via plotly
Frequently asked questions
What is the difference between DHARMa and MetaboAnalystR?
Both compete on the same themes — r-package — within Analytics. DHARMa and MetaboAnalystR are shipping at a similar cadence (velocity 0.0 vs 0.0, both within Sparkpulse's "active" band). See the at-a-glance table above for a side-by-side breakdown of velocity, recent sparks, and editorial themes.
Is DHARMa better than MetaboAnalystR?
Sparkpulse doesn't pick a winner — we score release velocity, not feature parity. DHARMa and MetaboAnalystR are shipping at a similar cadence (velocity 0.0 vs 0.0, both within Sparkpulse's "active" band). For your specific use case, the alternatives sections above list other Analytics products to evaluate alongside.
What are the best alternatives to DHARMa?
Top DHARMa alternatives in Analytics are ranked by recent ship velocity. Browse the "DHARMa alternatives" section above for the current picks, or visit /alternatives/dharma for the full list with editorial commentary on each.
What are the best alternatives to MetaboAnalystR?
Top MetaboAnalystR alternatives in Analytics are ranked by recent ship velocity. Browse the "MetaboAnalystR alternatives" section above for the current picks, or visit /alternatives/metaboanalystr for the full list with editorial commentary on each.