glyfun
glyfun is three releases old and has spent all of them chasing glyexp's container change.
Comparison · Analytics
constants vs glyenzy
A side-by-side editorial comparison of constants and glyenzy — release velocity, themes, recent moves, and the top alternatives to consider.
constants vs glyenzy: at a glance
What is constants?
The R package for CODATA constants rebuilt its symbol table on NIST's naming so future updates stop being hand work.
constants exposes the CODATA recommended values of the physical constants to R, as a data frame plus symbol lists that carry units, uncertainties, or both. The package reached 1.0.0 on the 2018 CODATA release and has shipped once since, purely to track a units package update. Its surface is small and its release cadence is bound to CODATA, which revises every few years.
What is glyenzy?
Glycan biosynthesis as a traceable enzyme graph, now including sulfation and gaps it can bridge.
glyenzy infers which enzymes could have produced a glycan and traces biosynthetic routes to it, backed by curated per-enzyme rules for human glycosyltransferases and, since 0.7.0, twelve sulfotransferases. Biosynthesis functions return typed network objects that keep their igraph interface while supporting layered DAG plots with glycan nodes and labelled enzyme edges. Where no concrete enzyme covers a step, bounded virtual transitions bridge the gap and are marked so users can see which edges are inferred rather than enzymatic.
constants vs glyenzy: editorial side-by-side
constants
0.0ANALYTICS
The R package for CODATA constants rebuilt its symbol table on NIST's naming so future updates stop being hand work.
◆ Current state
constants exposes the CODATA recommended values of the physical constants to R, as a data frame plus symbol lists that carry units, uncertainties, or both. The package reached 1.0.0 on the 2018 CODATA release and has shipped once since, purely to track a units package update. Its surface is small and its release cadence is bound to CODATA, which revises every few years.
◆ Where it's heading
The direction set at 1.0.0 was to stop being a curated convenience wrapper and become a mechanical mirror of NIST. Hand-crafted symbol names were replaced with NIST's own ASCII symbols, categories adopted NIST's, and uncertainty switched from relative to absolute — all framed by the maintainer as necessary to make future CODATA updates routine. On top of that the package gained a correlation matrix and optional integration with the quantities package, moving it from a lookup table toward something that can propagate uncertainty.
◆ Prediction
Having rebuilt the symbol table specifically so CODATA revisions become mechanical, the next substantive release most likely tracks a new CODATA dataset rather than adding API. The experimental correlated-value support, disabled by default at 1.0.0, is the one part these entries flag as unfinished.
glyenzy
6.3ANALYTICS
Glycan biosynthesis as a traceable enzyme graph, now including sulfation and gaps it can bridge.
◆ Current state
glyenzy infers which enzymes could have produced a glycan and traces biosynthetic routes to it, backed by curated per-enzyme rules for human glycosyltransferases and, since 0.7.0, twelve sulfotransferases. Biosynthesis functions return typed network objects that keep their igraph interface while supporting layered DAG plots with glycan nodes and labelled enzyme edges. Where no concrete enzyme covers a step, bounded virtual transitions bridge the gap and are marked so users can see which edges are inferred rather than enzymatic.
◆ Where it's heading
Two kinds of release alternate here. One is enzyme curation, a steady stream of rule corrections for the FUT, MAN1A and MGAT families and removals where an enzyme turned out to act only on glycolipids, which is the unglamorous accuracy work a rule-based inference engine lives on. The other is turning biosynthesis output into a first-class object: paths became networks, networks became typed with plotting support, and targets became a marked vertex attribute. The package moves in lockstep with its siblings, pinning glyrepr 0.13.0 and glymotif 0.17.0 as those refreshed their data and matching APIs, and the latest release already speaks glydraw 0.8.0's orientation values.
◆ Prediction
The paucimannose N-glycan support dropped in 0.7.0 is the obvious loose end, with users told to stay on 0.6.3, so a reinstated implementation is a plausible next move. Beyond that the virtual-step machinery is new enough that its heuristics, particularly the inferred step limits added in 0.8.1, should keep being tuned.
Alternatives to constants and glyenzy
Other Analytics products tracked by Sparkpulse, ranked by recent ship velocity. Each card links to a full editorial trajectory and lets you pivot into a head-to-head comparison with either constants or glyenzy.
glydet
glydet is rebuilding its glycan trait vocabulary on top of someone else's container.
glyexp
glyexp is retiring its own data container and handing the job to Bioconductor.
glymotif
A glycan motif matcher trading convenience wrappers for speed, strictness and explicit specs.
glyrepr
The type system the rest of the glycan stack is built on, being hardened one breaking change at a time.
glyanno
Glycan annotation stops depending on the database having seen the structure before.
See all constants alternatives → · See all glyenzy alternatives →
Recent activity from constants and glyenzy
Latest ship moves from both products, interleaved chronologically. ⚡ = editorial spark.
- 14d agoglyenzyStep limits inferred from the target glycan; MGAT4 and MGAT5 rules updated
- 17d agoglyenzyBiosynthesis results become typed network objects with layered DAG plots
- 23d agoglyenzySulfotransferases become first-class, and unsupported steps can be bridged ⚡
- 1mo agoglyenzyCompatibility with glymotif 0.17.0 and later
- 1mo agoglyenzyEnzyme data refreshed against glyrepr 0.13.0 structure data
- 1mo agoglyenzyCorrected rules for the MAN1A1, MAN1A2 and MAN1C1 mannosidases
- 5y agoconstantsCompatibility fix for units 0.7-0
- 5y agoconstantsconstants 1.0.0 ⚡
- 8y agoconstantsUnit handling fixes ahead of the 1.0.0 rebuild
Frequently asked questions
What is the difference between constants and glyenzy?
They serve adjacent needs but don't currently overlap on shipped themes. glyenzy is currently shipping more aggressively (velocity 6.3 vs 0.0), with 1 editorial sparks in the last 30 days against 0. See the at-a-glance table above for a side-by-side breakdown of velocity, recent sparks, and editorial themes.
Is constants better than glyenzy?
Sparkpulse doesn't pick a winner — we score release velocity, not feature parity. glyenzy is currently shipping more aggressively (velocity 6.3 vs 0.0), with 1 editorial sparks in the last 30 days against 0. For your specific use case, the alternatives sections above list other Analytics products to evaluate alongside.
What are the best alternatives to constants?
Top constants alternatives in Analytics are ranked by recent ship velocity. Browse the "constants alternatives" section above for the current picks, or visit /alternatives/constants-r for the full list with editorial commentary on each.
What are the best alternatives to glyenzy?
Top glyenzy alternatives in Analytics are ranked by recent ship velocity. Browse the "glyenzy alternatives" section above for the current picks, or visit /alternatives/glyenzy for the full list with editorial commentary on each.