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cfrnow vs n1qn1c

A side-by-side editorial comparison of cfrnow and n1qn1c — release velocity, themes, recent moves, and the top alternatives to consider.

Shared themes:r-package

cfrnow vs n1qn1c: at a glance

Featurecfrnown1qn1c
SectorAnalyticsAnalytics
Velocity score5.00.0
Sparks · 30d00
Top themesepidemiology, bayesian-modelling, cfr-estimation, r-packagenumerical-optimization, quasi-newton, thread-safety, memory-safety
Last editorial update5h ago1h ago
WebsiteVisit →Visit →

What is cfrnow?

A Bayesian real-time CFR estimator that now ships stratified fits and posterior-predictive checks

cfrnow estimates case fatality ratios from line-list data while an outbreak is still running, using a Bayesian mixture-cure survival model registered as an `epidist` model type. Three releases in a month took it from first public release to stratified, partially-pooled fits with posterior-predictive checking. It leans on `distspec` for delay parameterisation, which reached CRAN alongside the 0.2.1 patch.

Read the full cfrnow trajectory →

What is n1qn1c?

A Fortran-descended optimizer got thread-safe, then found two flags that never worked.

n1qn1c is a quasi-Newton optimization routine translated from Fortran to C, used as a solver backend by the nlmixr2 modeling stack rather than called directly by most users. Its two 2026 releases are a concentrated safety pass: global state converted to thread_local, static removed from local variables in the translated code, integer overflow guards added, and memory leaks closed in the R callback wrappers — plus the gcc-asan and valgrind fixes CRAN asked for.

Read the full n1qn1c trajectory →

cfrnow vs n1qn1c: editorial side-by-side

C
cfrnow
ANALYTICS
5.0

A Bayesian real-time CFR estimator that now ships stratified fits and posterior-predictive checks

◆ Current state

cfrnow estimates case fatality ratios from line-list data while an outbreak is still running, using a Bayesian mixture-cure survival model registered as an `epidist` model type. Three releases in a month took it from first public release to stratified, partially-pooled fits with posterior-predictive checking. It leans on `distspec` for delay parameterisation, which reached CRAN alongside the 0.2.1 patch.

◆ Where it's heading

The arc runs from producing a single corrected CFR number toward supporting a full model-checking workflow. 0.2.0 added the pieces a modeller needs to defend an estimate: replicate line lists replayed through the real-time truncation, an ascertainment-ratio correction for when fatal and non-fatal cases enter the line list at different rates, and per-group CFRs from `brms` formulas. Delay coverage widened from LogNormal and Gamma to Weibull in the same release.

◆ Prediction

Expect the next release to keep widening covariate and pooling support rather than adding new outcome types, since every 0.2.0 addition extended the existing formula interface instead of replacing it.

N
n1qn1c
ANALYTICS
0.0

A Fortran-descended optimizer got thread-safe, then found two flags that never worked.

◆ Current state

n1qn1c is a quasi-Newton optimization routine translated from Fortran to C, used as a solver backend by the nlmixr2 modeling stack rather than called directly by most users. Its two 2026 releases are a concentrated safety pass: global state converted to thread_local, static removed from local variables in the translated code, integer overflow guards added, and memory leaks closed in the R callback wrappers — plus the gcc-asan and valgrind fixes CRAN asked for.

◆ Where it's heading

The package is being hardened for use inside a parallel modeling framework rather than extended. The audit that produced the thread-safety work also surfaced two plain bugs in features users would have assumed worked: restart = TRUE left the mode at 2 instead of 3 because of a typo, and assign = TRUE referenced the wrong field name so the compressed Hessian was never written to the supplied environment. Earlier work points the same direction — the 6.0.1-12 function-pointer interface exists so nlmixr2est does not need resubmission when this package changes.

◆ Prediction

Expect further memory-safety and sanitizer work rather than algorithmic change; a Fortran-translated numerical core under CRAN's checking regime generates that kind of release indefinitely.

Alternatives to cfrnow and n1qn1c

Other Analytics products tracked by Sparkpulse, ranked by recent ship velocity. Each card links to a full editorial trajectory and lets you pivot into a head-to-head comparison with either cfrnow or n1qn1c.

See all cfrnow alternatives → · See all n1qn1c alternatives →

Recent activity from cfrnow and n1qn1c

Latest ship moves from both products, interleaved chronologically. ⚡ = editorial spark.

  1. 5d agocfrnowdistspec dependency moves to CRAN
  2. 5d agocfrnowStratified CFR fits, Weibull delays, posterior-predictive checks
  3. 1mo agocfrnowFirst release: real-time CFR from a Bayesian mixture-cure model
  4. 4mo agon1qn1crestart and assign flags fixed; sanitizer issues cleared
  5. 4mo agon1qn1cGlobal state converted to thread_local
  6. 1y agon1qn1cFunction-pointer API decouples nlmixr2est releases

Frequently asked questions

What is the difference between cfrnow and n1qn1c?

Both compete on the same themes — r-package — within Analytics. cfrnow is currently shipping more aggressively (velocity 5.0 vs 0.0), with 0 editorial sparks in the last 30 days against 0. See the at-a-glance table above for a side-by-side breakdown of velocity, recent sparks, and editorial themes.

Is cfrnow better than n1qn1c?

Sparkpulse doesn't pick a winner — we score release velocity, not feature parity. cfrnow is currently shipping more aggressively (velocity 5.0 vs 0.0), with 0 editorial sparks in the last 30 days against 0. For your specific use case, the alternatives sections above list other Analytics products to evaluate alongside.

What are the best alternatives to cfrnow?

Top cfrnow alternatives in Analytics are ranked by recent ship velocity. Browse the "cfrnow alternatives" section above for the current picks, or visit /alternatives/cfrnow for the full list with editorial commentary on each.

What are the best alternatives to n1qn1c?

Top n1qn1c alternatives in Analytics are ranked by recent ship velocity. Browse the "n1qn1c alternatives" section above for the current picks, or visit /alternatives/n1qn1c for the full list with editorial commentary on each.